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The secret to producing large numbers of stem cells more efficiently may lie in the near-zero gravity conditions in space
A new paper led by Cedars Sinai and published in the peer-reviewed journal Stem Cell Reports highlights the key opportunities for expanding space stem cell manufacturing discussed at the 2020 Space Biomanufacturing Symposium
Biomanufacturing is a type of stem cell production.
Stem cell biologist Dr.
He said: "In the past 20 years, regenerative medicine has made significant progress, and space technology has also made exponential progress, providing new opportunities for entering and commercializing space
According to Cedars Sinai's paper, attendees at the December Virtual Space Symposium identified more than 50 potential business opportunities for biomanufacturing work in space
The first is disease models.
Researchers have found that once the body is exposed to a low-gravity environment for a long time, it will accelerate bone loss and aging
Sharma, the corresponding author of the paper, said: “This work can not only help astronauts, but also guide us to create bone structures or skeletal muscle structures for the treatment of diseases such as osteoporosis, as well as other forms that humans experience on Earth.
Another highly discussed topic at the seminar was biomanufacturing, which uses manufacturing processes to produce materials such as tissues and organs
One of the main problems in producing these materials on Earth is the density caused by gravity, which makes it difficult for cells to expand and grow
The third category is related to the production of stem cells and understanding how some of their basic properties are affected by microgravity
Understanding some of the effects of space flight on stem cells, it is possible to find a better way to create a large number of cells without gravity
Sharma said: "Although we are still in the exploratory stage of some research, this is no longer the field of science fiction
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