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    Home > Medical News > Medical Science News > Gemini virus promotes viral infection through autophagy factors

    Gemini virus promotes viral infection through autophagy factors

    • Last Update: 2021-10-19
    • Source: Internet
    • Author: User
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    Gemini virus promotes the mechanism of virus infection through autophagy factors


     Gemini virus promotes the mechanism of virus infection through autophagy factors


    Gemini viruses have caused devastating damage to a variety of cash crops and food crops, severely restricting agricultural production in China and the world


    As an important selective autophagy receptor, NBR1 can mediate specific proteins into the autophagy pathway for degradation


    As an important selective autophagy receptor, NBR1 can mediate specific proteins into the autophagy pathway for degradation


    Further research found that NBR1 competes with another host factor NbRFP1 to bind βC1


    However, βC1 uses the granular structure formed by interaction with NBR1 to avoid the degradation of host plants, thereby increasing the protein accumulation level of βC1 and promoting virus infection


    NBR1 mutant genetic material can be resistant to a variety of geminiviruses and plant RNA viruses, indicating that NBR1 may be a broad-spectrum susceptible gene to plant viruses


    Related paper information: https://doi.


    https://doi.
    org/10.
    1371/journal.
    ppat.
    1009956
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