Genes associated with personality are also associated with mental illness, as recommended in the Nature Genetics paper.

Through correlation analysis, the researchers found that certain chromosomal regions were associated with both personality traits and mental illness.
source Ars Technica Translator Yan Bing Review chen Yuxin's innitive genetic and the day-to-day experience will shape our personality and mental health in a variety of ways, both of which are equally important, and the former is more elusive.
In a recent genetic analysis study, researchers identified six genome fragments in a complex human genetic map related to the top five personalities (extrophic, neurotic, affinity, due diligence, and openness), some of which can affect both personality and mental health, such as boasting or being cautious in front of strangers, and whether they are susceptible to mental illnesses such as schizophrenia, attention deficit disorder (ADHD).
specifically, the researchers found genetic associations between extrophic and ADHD, neuroticism and depression, openness and schizophrenia and biplex disorder.
new findings have deepened our understanding of mental health and may help diagnose and treat mental illness.
study, conducted by the University of California, San Diego, was published in the journal Nature Genetics.
60,000 genetic samples screened in the study were provided by consumer genomics firm 23andMe, while the Genetics of Personality Consortium provided a database of about 8,000 genetic samples.
the data, the researchers tried to find a link between specific DNA fragments, personality and mental illness.
psychologists often use the aforementioned big five personality models when studying personality, which can cover almost all aspects of personality description and rate a person's personality by scoring each of these five traits.
early studies of twins and family linees showed that about 40 percent of differences in personality test results could be explained by genetic factors.
combined all genetic and personality analysis data, the researchers found a strong correlation between neuroticism and chromosomal region 8p23.1.
the chromosomal region is known to encode genes associated with congenital immunity and the nervous system, and early studies have found that the region is associated with cancer and developmental neuropsychiosis.
and neurotic are characterized by anxiety, depression and mood instability, and the findings suggest mechanisms.
researchers also found a strong correlation between extroversion and chromosomal region 12q23.3.
that 12q23.3 is associated with bipolar disorder, suggesting that the region is involved in regulating personality and temperament.
the association analysis, the researchers found a significant genetic correlation between neurotics and depression, extroverts and ADHD, which they believe suggests is likely to be one of the extroverted variants.
, the study also found that mutations in the L3MBTL2 gene were associated with both neuroticism and schizophrenia, supporting a previously identified link between neuroticism and schizophrenia in group studies.
MTMR9 gene mutations are associated with the susceptibility of extrogenic and antipsytrotic drugs.
, the researchers found no significant genetic correlation between conscientiousness, education, and academic achievement.
, the study found that certain genetic factors can affect both personality traits and mental illness.
despite the large sample size in the study, the researchers believe it is not enough to make a statistical analysis of some of the rare genetic traits that may be associated with personality and disease.
, the findings are enough to give us greater hope for an analysis of the genetic link between personality and mental illness.
basic information of the paper (title) Genome-wideanalyses for personality traits identify six genomic loci and show correlationswith psychiatric disorders Min-Tzu Lo, David A Hinds, Joyce Y Tung, Carol Franz, Chun-Chieh Fan, etc . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . However, the underlying genetic determinants are largely unknown. We identifiedsix genetic loci, including five novel loci, majorly associated withpersonality traits in a meta-analysis of genome-wide studies association (N s123,132-260,861). Of these genome-wide large loci, extraversion wasassociated with variants in WS CD2 and near PCDH15, and neuroticism withvariants on chromosome 8p23.1 and in L3 MBTL2 . We performed a principal componentanalysis to extract major dimensions underlying genetic variations among fivepersonality traits and six psychiatricdisorders (N s 5,422-18,759). The first geneticdimension slyd personality traits and psychiatric disorders, except thatneuroticism and open to experience was clustered with the disorders. Highgenetic correlations were found between extraversion and attention-risk-hyperactivitydisorder (ADHD) and between open and schizophrenia and bipolar disorder. The second genetic dimension was closely aligned with extraversion-introversionand grouped neuroticism with internalizing psychopathology (e.g., depression oranxiety). Source: Ars Technica.