Great news! Clinical application of plasma products of biotherapy new crown in China

Recently, novel coronavirus pneumonia came to the forefront of heavy news Sinopharm China biology has completed the collection of plasma from some rehabilitation patients, and carried out the preparation of new coronavirus special plasma products and special immunoglobulin After strict blood biological safety test, virus inactivation, antiviral activity test, etc., we have successfully prepared the special plasma for clinical treatment, which has been used in Wuhan Institute of biological products of China biology, Wuhan blood products Co., Ltd of State Pharmaceutical Group, the first people's Hospital of Jiangxia District, Wuhan Blood Center, Wuhan Institute of virus of Chinese Academy of Sciences, China food and drug inspection With the close cooperation of the Research Institute, we put into clinical treatment of severe patients Novel coronavirus pneumonia patients have been collected in Wuhan since January 20th After a series of preparations and coordination, China's biology team set up a special team to mobilize related equipment and raw materials In February 8th, a novel coronavirus pneumonia diagnosis and treatment plan (trial version fifth) was taken as the guide The first time in Jiangxia District First People's Hospital, 3 new critical plasma treatment for critically ill patients were launched At present, more than 10 critically ill patients have been treated with the follow-up hospital Clinically, 12 to 24 hours after treatment, the main inflammatory indicators in the laboratory decreased significantly, the proportion of lymphocytes increased, the key indicators such as blood oxygen saturation and viral load improved comprehensively, and the clinical signs and symptoms improved significantly The novel coronavirus pneumonia plasma products are the plasma containing highly effective new crown virus specific antibodies donated by the rehabilitative patients They are treated by virus inactivation, and neutralized by the new crown virus neutralizing antibody and detected by multiple pathogenic microorganisms, and are used for the treatment of critical patients with new crown pneumonia Experts say that novel coronavirus pneumonia can cure and recover the specific antibodies against the new crown virus, which can kill and eliminate the virus At present, in the absence of vaccines and specific therapeutic drugs, the most effective method is to use this special plasma product to treat the new coronavirus infection, which can significantly reduce the mortality of critical patients China's head of biological research and development said that the collection, preparation and series of detection process of the new coronavirus plasma have good safety, mature preparation process and short time At present, the "preparation of specific plasma and specific immunoglobulin for 2019-ncov patients in the recovery period" project undertaken by China Bio has been approved by the national key research and development plan "public safety risk prevention and control and emergency technical equipment" organized and formulated by the Ministry of science and technology of the people's Republic of China, and has been strongly supported by the Department of science and technology of Hubei Province, the health and Health Commission and other departments China China China attaches great importance to novel coronavirus, and has set up a new research team for its special research team It was led by the vice director of the Chinese Pharmaceutical Biotechnology Association, the chief scientist of the 863 Program vaccine project and Yang Xiaoming, the Chinese biological director, and the focus of the work was launched in January 20th New coronavirus related diagnostic reagents, new coronavirus special plasma products, new coronavirus special immunoglobulin, new coronavirus inactivated vaccine, new coronavirus recombinant genetic engineering vaccine, new coronavirus monoclonal antibody and other scientific research key problems Among them, Zhongsheng Shanghai Jienuo is the first to develop a new coronavirus nucleic acid molecular detection kit, and the first to obtain the registration certificate issued by the State Drug Administration; for the key epidemic areas in Wuhan, Hubei Province, a front-line headquarters to fight against the epidemic was established, and Dr Duan Kai, general manager of Wuhan Institute of biological products of China, is responsible for mobilizing and coordinating the first-line resources In the Efforts should be made to promote and actively coordinate the scientific research of the new crown plasma products, new crown virus inactivated vaccine, monoclonal antibody and other projects China biology attaches great importance to the research and development work related to new coronavirus, arranges 400 million research and development funds in advance, makes use of the existing technical platforms of China biology, works closely with the National Center for disease control, Wuhan Institute of Virology of the Chinese Academy of Sciences and hospitals in Wuhan and other relevant units, and receives strong support from the National Health Commission, the State Food and drug administration, as well as departments in Hubei Province and Wuhan city China Bio will actively fulfill its social responsibility, fully promote the research and development of prevention, treatment products and other projects, and ensure that the research work is accurate, orderly and efficient 37