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    Home > Biochemistry News > Microbiology News > Green (p.aeruginosa)

    Green (p.aeruginosa)

    • Last Update: 2021-01-24
    • Source: Internet
    • Author: User
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    of green pus (). p.aeruginosa ), a genus(pseudomonas) , is widely distributed in nature and in the skin, intestines and respiratory tract of normal people, is one of the more common clinically pathogenic bacteria. Sizes1.5to 3.0 × 0.5to 0.8um ,g- bacteria. One end of the body usually has a whip hair, lively movement. No buds, rice liquid strains have a sugary membrane or glycogen, with anti-swallowing effect. In ordinary
    culture
    growth on the base of good, specialized oxygen demand. The pattern of fallage is different, most diameters 2to 3mm , the edges are not aligned, flat and moist. A transparent
    is formed
    plate of the agar plate in the blood cell. Liquid culture is cloudy and formed. Green pus bacteria can produce two kinds of water-soluble pigment: one is chloroprosterin, blue-green pyridoxic, non-fluorescent, with antibacterial effect. The other is luciferin, which is green. Eerepsis is only produced by Eocyrobacteria, so it is of diagnostic significance. However, the mutant strains screened after the widespread use of effective antibiotics often lose their ability to synthesize.Decomposition
    protein
    ability is very strong, and fermentation sugar capacity is low, decomposition of glucose, acid production is not gas-producing, do not break down glycol, lactose and sucrose, can liquefy gelatin. Break down urea, do not form radon, oxidase test positive, can use radon. Green pus bacteria have bacteriaoantigen
    and whiplashhantigen.theantigen contains two ingredients, endotoxin and primary endotoxin protein. The primary endotoxin protein is a highly molecular, low toxicity, immunogenic protective antigen, not only found in different
    sexual
    type of green pus bacteria, but also widely found in other bacteria of the genus Pneumococcal, E. coli, Vibrio cholerae and other g- bacteria, is a good cross-protective antigen.Green pus can produce a variety of toxic substances, such as endotoxins, exotoxins a , elastinase, collagenase, trypsin, trypsin, etc. , of which the external toxin ais the most important. Green pus extratoxin ais a thermally unstable single chain
    peptide
    , molecular weight of about 66 , 000 , treated with formaldehyde or dialdehyde can be detoxifyed as a toxin, and is neutralized by specific antitoxins. Strong toxicity, injected into animals, the main target organ liver can appear cell swelling, fat degeneration and necrosis; The a of exotoxins is somewhat similar to diphtheria toxins, i.e. the extension factor 2 (ef to 2 ) on the icingosome is eventually insulate, inhibiting protein synthesis in host cells, but the process is different. In addition, exotoxins a diphtheria toxins differ in protein structure, immunogenicity, whip cells, and sensitive animals. Bacillus green infections can occur in any part and tissue of the body, commonly found in burn or trauma sites, the middle ear, cornea, urethra and respiratory tract. It can also cause endoarthritis, gastroenteritis, pus and even sepsis. After infection, patients can produce specific antibodies
    antibodies
    , has a certain anti-infection effect. The application of anti-egret immunosepsis serum can reduce the occurrence and death rate of secondary sepsis in patients. Specimens are desirable for invasion oozing, pus, urine, blood, etc. Separation culture, according to the characteristics of the fallon, pigmentation and
    bio
    bio-chemical reactions to identify. If necessary, it can be confirmed with a serological test. Treatment uses penicillin, aminoquine, cytocytoplasmytes and other antibiotics. Combined medication can reduce the production of drug-resistant strains. Green pus is a common pathogen of hospital infection, so disinfection measures play an important role in preventing infection. Because of the many types of green pus bacteria, and toxicity-related substances are also a variety, so the ideal seedlings are still under development.
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