Green processing improves quality and efficiency (multiple figures)

First, the basic situation of Chinese herbal medicine industry After the founding of the people's Republic of China, China has vigorously developed the cultivation and cultivation of traditional Chinese medicine Of the annual supply of 3 million tons of traditional Chinese medicine, 70% comes from cultivation and cultivation, which basically guarantees the raw materials for the traditional Chinese medicine industry and the prescription for doctors It can be summarized from four aspects: the basic establishment of the production system of traditional Chinese medicine; the basic formation of the market distribution pattern of traditional Chinese medicine; the continuous improvement of the quality standards of traditional Chinese medicine; and the considerable progress of the production technology of traditional Chinese medicine Second, there are problems in the production safety of traditional Chinese medicine First, the supply guarantee capacity needs to be strengthened On the whole, the dependence on wild resources has declined However, due to factors such as heavy mining, light breeding, over excavation and ecological environment damage, some wild medicinal materials resources are endangered and in short supply, and some genuine medicinal materials production areas are shrinking Second, the production level is relatively backward At present, the development level of traditional Chinese medicine agriculture is not only seriously incompatible with the rapid development of traditional Chinese medicine industry, or even far behind the overall development level of China's agriculture The production organization level is low, the primary processing level of the production area is backward, and the overall scientific and technological level of traditional Chinese medicine is backward Third, the quality of medicinal materials is not stable, the phenomenon of blooming everywhere and blind introduction is widespread, the authenticity of medicinal materials is significantly reduced, the abuse of pesticides, illegal addition and counterfeiting make the quality of some medicinal materials, especially valuable medicinal materials significantly reduced, the lack of quality classification standards, the unreasonable pricing and bidding mechanism of medicinal materials, the quality standards of traditional Chinese medicine have been significantly improved, but the production supervision of traditional Chinese Medicine Fuzzy responsibilities, serious lack of market supervision and local protection are all important factors leading to the decline of the quality of traditional Chinese medicine and market confusion Fourth, the order of market circulation needs to be standardized At present, the circulation of traditional Chinese medicine mainly depends on the traditional market However, the circulation of fake and inferior Chinese medicine, non-medical parts of Chinese medicine and polluted Chinese medicine, dyeing and weight gain, adulterating fake Chinese medicine and toxic Chinese medicine seriously affects the safety of drugs Hoarding and malicious speculation lead to sharp fluctuations in the price of Chinese medicine, which seriously threatens the stable and coordinated development of production and marketing Exhibition Third, we should work together to improve the safety and quality of traditional Chinese medicine production First, we need to accelerate the construction of standardized, large-scale and industrialized production bases for commonly used bulk medicinal materials and breeding bases for endangered and scarce medicinal materials According to the authenticity, high quality and production suitability of traditional Chinese medicine, the production areas of traditional Chinese medicine should be scientifically arranged, the technological progress of traditional Chinese medicine agriculture should be accelerated, and the research on endangered and scarce traditional Chinese medicine and its substitutes should be increased, so as to meet the needs of pharmaceutical industry and clinical practice Second, we should strengthen the construction of quality standards and evaluation system of traditional Chinese medicine We will speed up the revision and improvement of the national standard system of traditional Chinese medicine with Chinese Pharmacopoeia as the main body, improve the control level of drug safety, actively explore the establishment of rapid detection methods for traditional Chinese medicine, comprehensively establish a new system and mode of overall control quality suitable for the characteristics and characteristics of traditional Chinese medicine, and realize the leading international standard of traditional Chinese medicine standard Third, we should vigorously carry out the rectification of the Chinese herbal medicine market, standardize the market order, and strengthen supervision and management The State Food and drug administration has been carrying out the special action of "two strikes and two constructions" for two months Relevant departments around the country have taken active actions Illegal behaviors have been curbed to a certain extent, and the market order has been improved to a certain extent 1、 The way of deep processing of traditional Chinese Medicine Chinese Herbal Pieces: optimize varieties, standardize planting, improve the processing level of Chinese herbal pieces, extracts and production level of Chinese patent medicine; vigorously cultivate large varieties of Chinese herbal pieces, extracts and Chinese patent medicine; make full use of Zhejiang's rich resources of Chinese herbal medicine; expand the brand advantages of "eight flavors of Zhejiang"; strengthen other advantages, such as the large-scale and deep processing of Chinese herbal medicine, such as the price of black medicine, the price of Dendrobium candidum, and the price of saffron Through special support, industry restriction, merger and acquisition integration, the situation of small scale, backward equipment and low production quality management level of more than 70 pieces of decoction enterprises in our province has been changed, and the way of large-scale processing of pieces of decoction has been resolutely taken Extract of traditional Chinese medicine: establish a complete and effective standard system, including the source of traditional Chinese medicine, extraction and separation, R & D and production, and quality control Traditional Chinese medicine formula granules: Traditional Chinese medicine formula granules are powder and granule products which are extracted, concentrated and dried instantly by modern scientific and technological means It can be used as a supplement between Decoction and traditional Chinese medicine Take the broad road of combining traditional Chinese medicine for treatment with health care, rehabilitation and food, and take the broad road of combining traditional Chinese medicine for human use with traditional Chinese medicine for feed, animal use and agricultural use 2、 Make Zhejiang traditional Chinese medicine industry bigger and stronger 1 Prevent the exhaustion of rare medicinal materials resources 2 Prevent the low-end export of running quantity type, avoid repeating the mistakes of chemical APIs, establish and improve the coordination mechanism, and prevent the rare and key traditional Chinese medicine varieties and brands in our province from being abused 3 Pay attention to the ecological balance of large-scale cultivation of traditional Chinese medicine, and vigorously promote the successful pharmaceutical and vegetable cycle in Lishui and other places (such as Yuanhu price or Zhebei price or saffron price / rice, Qianhu price / corn and other interspecies interplanting) efficient production mode 4 Push forward the development of traditional Chinese medicine breeding to ecological circular agriculture, and vigorously improve the comprehensive utilization and development level of medicinal resources First, the factors affecting the quality of traditional Chinese medicine The quality of traditional Chinese medicine is produced The influencing factors include: the base environment and the quality of medicinal materials, the original and excellent varieties and the quality of medicinal materials, the production methods and techniques and the quality of medicinal materials, the production process management and the quality of medicinal materials, the collection and processing methods and the quality of medicinal materials, the storage methods and conditions of medicinal materials and the quality of medicinal materials A Base environment and quality of medicinal materials: for example, the price of Astragalus and liquorice There are many places of origin of the same kind of medicinal materials with different environments The air environment, soil quality and irrigation water quality of the base meet the environmental quality requirements of gap production base B Basic species, excellent varieties and quality of medicinal materials: plant basic species and cultivated varieties, also take the prices of three kinds of liquorice and scutellaria collected in Pharmacopoeia as examples C Production methods and techniques and quality of medicinal materials: the effects of production techniques on the quality of medicinal materials include the types and methods of fertilization, and irrigation techniques D Production process management and medicine quality: production mode can be divided into wild and cultivated In the production process: (1) heavy metals and agricultural residues exceed the standard: the international environmental protection organization Greenpeace issued the investigation report on traditional Chinese medicine: pesticide pollution of traditional Chinese medicine (65 samples in nine cities in China, 48 containing agricultural residues, accounting for 70%), 32 of which detected more than 3 kinds of different agricultural residues, and 9 kinds of agricultural residues reached more than 20 kinds About 30% of the Chinese herbal medicines exported to South Korea contain more heavy metals than the standard of South Korea, and the mercury content of some "compound aloe price Capsules" exported from China to the UK is said to exceed the British standard by 117000 times （2） External pollution: pest control, fertilizer application Second, the collection and quality of traditional Chinese medicine Taking honeysuckle price as an example, considering the output and quality of honeysuckle price in six stages of development, it is most suitable to pick honeysuckle from the second white price stage to the big white price stage The content of chlorogenic acid and Luteolin in honeysuckle price in the second white price stage and the big white price stage are significantly higher than that in the conventional drying treatment after microwave killing and drying Third, the processing method and the quality of traditional Chinese medicine Processing of the origin of traditional Chinese medicine: picking and dressing; steaming, boiling, scalding; washing and soaking; sweating; drying; selecting grades Taking honeysuckle price drying as an example: Honeysuckle price in different flowering period was significantly higher than that in the second white period after microwave treatment and conventional drying The results showed that the interaction between drying method and different flowering period had significant effect on chlorogenic acid and rutin content Fourth, the discussion of fresh slicing technology in the origin of traditional Chinese medicine The appearance of price slices of Anemarrhena asphodeloides with different water content, the comparison of four kinds of medicinal active components in price slices of Anemarrhena asphodeloides with different water content, the appearance of fresh slices of Glycyrrhiza asphodeloides with different water content, the influence of slices with different water content on the content of total flavonoids and saponins in price of Glycyrrhiza asphodeloides, and the influence of slices with different water content on the content of Glycyrrhiza asphodeloides and glycyrrhizin.