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    Home > Biochemistry News > Microbiology News > Herpes Simplex Virus Life Cycle and the Design of Viral Vectors

    Herpes Simplex Virus Life Cycle and the Design of Viral Vectors

    • Last Update: 2021-01-26
    • Source: Internet
    • Author: User
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    Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) are doublestranded
    DNA
    viruses with a genome size of 152 kbp. The genome consists of two unique regions, U
    L
    (long) and U
    s
    (short), flanked by repeated sequences (Fig. 1 ; for review,
    see
    ref.
    1
    ). The two viruses are closely related, and both infect humans, producing mucocutaneous sores that are predominantly facial in the case of HSV-1 and genital in the case of HSV-2.
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