Herpes Simplex Virus Life Cycle and the Design of Viral Vectors
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Last Update: 2021-01-26
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Source: Internet
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Author: User
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Herpes simplex viruses types 1 and 2 (HSV-1 and HSV-2) are doublestranded
DNA
viruses with a genome size of 152 kbp. The genome consists of two unique regions, U
L
(long) and U
s
(short), flanked by repeated sequences (Fig. 1 ; for review,
see
ref.
1
). The two viruses are closely related, and both infect humans, producing mucocutaneous sores that are predominantly facial in the case of HSV-1 and genital in the case of HSV-2.
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