High-pressure oxygen-combined antibiotics to treat infections caused by neuroregulators

Ref:Bartek J Jr,et al.Stereotact Funct Neurosurg.
 2018 Apr 3doi: 10.1159/000486684(Epub ahead of print)theNeuromodulation is an implanted medical device that provides injections or electrical stimulation of nerve tissue drugs to reduce symptoms or promote neurofunction recoveryThese instruments include electrophysiological generators such as deep brain stimulation, spinal cord stimulation and vagus nerve stimulation, as well as cobweb subcavity injection pumps, etcIn neuro-control therapy, the infection associated with instrument hardware implantation is the main cause of regulator removalHyperbaric oxygen therapy (HBOT) is a safe and effective aid for the treatment of spontaneous brain abscesses, complex wound infections, etcThe literature reports that HBOT helps control central nervous system infections and improves patients' clinical prognosis without removing buried hardwareJiri Bartek Jr, neurosurgery at Karolinska University Hospital in Sweden, and others studied the effects of hyperbaric oxygen in combination with antibiotics to treat infections caused by neuroregulators, published online in April 2018 in The Stereotact Funct Neurosurgbetween 2002 and 2015, the authors treated 12 infections associated with nerve regulator implantation with antibiotics and HBOT at the authors' hospitalTwo patients had two separate infections of this typeThe study assessed issues such as antibiotics and HBOT for the treatment of infections and the removal of regulators12 of the 14 cases of instrument hardware-related infections (86%) were successfully cured by antibiotics in combination with HBOT and the implants were not removedTwo cases were treated with HBOT in two separate infections, and the infection was controlled, eventually retaining the regulatorTwo cases were removed from the implanted instrument hardware after HBOT treatment failedNo long-term infection occurred in all patientsDuring treatment, there were two complications related to hyperbaric oxygen therapy, one of which was two months after the end of HBOT treatment, six patients with permanent double-sided cataracts, a common complication of HBOT treatment, and the other, two months after the end of HBOT treatment, the Mtronic Synchromed II pump used for infusion of baclofen had to be removed due to a lack of re-capacity due to air pressure damageTable 1Treatments and outcomes for hardware-related infections in 12 patientsauthors point out that HBOT combined with antibiotics has good effect on infectioncause of nerve regulator hardware implants, which can reduce the incidence of removal of implants and interruption of neuroregulatory treatment(
Xiaoxincompiled, Professor Wang Zhiqiu,of Huashan Hospital, Fudan University,and Professor Chen , Professor Chen Jicheng, affiliated with Fudan University, .