How can I avoid infection by replacing the DBS pulse generator surgery?

Ref: Pepper J,et alJNeurosurg. 2016 Jun 17: 1-8deep brain stimulation (DBS) has been widely used in the treatment of Parkinson's disease, dystonia and tremorsRecent research by Joshua Pepper, a functional neurosurgery at the University of London's Institute of Neurology, and others have found a significant increase in the risk of infection when replacing implantable pulse generators( IPG)To this end, the team began in January 2012 to adopt new perioperative treatment measures to reduce the incidence of infection in replacement IPG surgeryThe results were published in June 2016"J Neurosurg"onlinethe authors used patients who underwent IPG surgery before January 2012 as a control group, and prospective Patients with IPG replacement surgery from January 2012 to December 2014 as a study groupIn the study group, all patients were tested for methicillin-resistant Staphylococcus aureus (MRSA) in the skin and nasal cavity prior to surgeryIf the patient is unable to participate in the preoperative examination, or MRSA test positive, or before MRSA test positive, or because of MRSA infection and delayed surgery, are required to receive MRSA treatment: 6 days, with 4% chlorpyrifos daily bath; Before replacing IPG, antibiotics are routinely used to prevent infection, such as MRSA-positive plus traculainen, 6mg/kg, intravenous drug usePlace in the cavity of the IPG and rinse with 1mg/ml vancomycin solution 20 mlAfter surgery, antibiotic intravenous drips continue 3 times, 10-14 days after the linea total of 171 patients with 195 IPG replacement operationsIn the control group of 80 patients, 94 IPG replacement operations, the average age of the patients was 48 to 20 years old, 48% were male In 91 patients in the study group, 101 IPG replacement s/ patients had an average age of 54 to 15 years and 56% were male There was no significant difference in the incidence of gender, DBS surgical indications, deep brain targets, and diabetes The study group followed up an average of 24 to November without any infection complications, the control group followed up an average of 73 to 26 months, 6 patients with secondary infection, and the infection rate was 7.5% per total patient s 8.5% per operating total (p-0.003) (Figure 1) No adverse events occurred during the implementation of the new perioperative treatment Figure 1 Comparing the infections of the two groups of patients in summary, in the replacement of DBS implanted pulse generator surgery, the use of the research developed by the perioperative treatment method, is conducive to control the occurrence of infection, avoid unnecessary resurgery, but also reduce the treatment cost of DBS (The second hospital affiliated with Zhejiang University
Wang Yongjie compiled, Dr Zheng Feng
of the School of Medicine of Cologne University, Germany, review, "Outside the God Information" editor-in-chief, Fudan University affiliated Huashan Hospital Chen Jicheng Professor Final Appeal) related review