How does the immune system "remove" RNA viruses?

RNA virus? I haven't heard of it.
but hepatitis C virus (HCV), HIV (HlV), SARS virus, Ebola virus (EBV), avian influenza virus, influenza virus... Must be like thunder.
them, they belong to THE RNA virus.
innate immune response is the body's first line of defense against the virus.
how exactly the immune system "clears" the RNA virus remains a mystery in the academic world.
, a new study by Zhu Haizhen, a team at the Institute of Pathogen Biology and Immunology of Hunan University's School of Biology, has discovered a working mechanism that immunizes against RNA viruses, and the results have recently been published in the internationally renowned journal Virology.
" resistance to the virus can be seen as a battle between the immune system and the virus. first,
, patternrecognition receptor sororrig-I or MDA5 in host cells (virus-invading cells) acts as 'scouts', which, after identifying the invading virus, transmits the intrusion signal to the 'combatant' MAVS, allowing it to remove the virus under the instructions of the 'commander' of TRIM21.
," Zhu said.
their study found that when "commander" TRIM21 is expressed highly, it encourages MAVS to increase its ability to recruit "another series of combatants" kinase TBK1, which ultimately enhances the immune response and eliminates the virus.
, on the contrary, when TRIM21 is low,MAVS's ability to recruit TBK1 is weakened, making immunity weaken and the virus from being effectively eliminated.
this shows that TRIM21 can promote the removal of the virus by effectively regulating MAVS and promoting the removal of the virus by the innate immune response.
the discovery of this mechanism, it is expected to find drug targets for people with chronic viral infection, promote drug research and development, and provide a theoretical basis for the development of related vaccines.
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