How the memory of fear is trapped in the brain

Researchers at Linkping University in Sweden have discovered a biological mechanism that increases the intensity
of fear memory stored in the brain.

The ability to experience fears is essential for escaping life-threatening situations and learning to avoid them in the
future.

Certain areas of the brain are particularly important
for processing fear-related memories.

"We know that the network of nerve cells that connect the frontal lobe and the amygdala is associated
with fear responses.

However, the molecular mechanisms have remained unknown
.

In order for new memories to last, they must be stabilized and preserved as long-term memories
.

"We have identified a mechanism whereby increased network activity between the frontal lobe and amygdala increases the learned fear response
.

The researchers also identified genes
that are affected when PRDM2 levels are reduced.

"People with anxiety disorders may benefit
from treatments that weaken or eliminate fearful memories.