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    Home > Biochemistry News > Peptide News > How to improve the antitumor ability of peptides?

    How to improve the antitumor ability of peptides?

    • Last Update: 2019-08-09
    • Source: Internet
    • Author: User
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    Tumor is a common disease, which is a serious threat to human health In many developed countries, the death rate of malignant tumor is second only to that of heart disease; in China, malignant tumor is also the main cause of death Tumor is formed by over differentiation or abnormal differentiation of normal cells in the body under certain factors The etiology of tumor is very complex, which is the result of many factors such as heredity and environment The occurrence and development of tumors are closely related to the immune system The tumor is like a thief, and the immune system is like a policeman If the thief escapes the police's surveillance, the thief will go unpunished When the professional level of the police is improved, the ability to identify thieves is enhanced and the shooting method is more punctual, and the thieves will be arrested or eliminated Therefore, to improve the professional level of the police is the key to fundamentally treat cancer Although tumor thief has many ways to strengthen himself, turtle peptide is a large force They have many ways to deal with tumor Thief: 1 Direct inhibition of tumor growth Among the large forces of turtle peptide, a small one is a special force with "tumor suppressor gene", which has a very strong ability Among many kinds of multiple tumors, one kind of peptide is undercover, which can enter tumor cells and activate "tumor suppressor gene", a special force, to make tumor cells die early; another kind of peptide, which is also a very powerful undercover, can enter into tumor cells and let "special forces with external support" deal with tumors together with the original special forces, so as to achieve the effect of inhibiting tumor growth 。 2 Inhibition of tumor metastasis The tumor thief also wants to achieve his own goal by changing his face He is a particularly sticky villain He will meet his friends outside the cell and run away after changing his face But turtle peptide can deceive the tumor thief The tumor thief regards peptide as an accomplice and gets cheated He can't finish the work with the accomplice he thinks 3 Inhibition of tumor angiogenesis The growth and escape of the primary tumor force depends on the "road" of blood vessels The roads can be built densely The tumor can not only get strong nutrition and oxygen through these roads, but also transfer its own thief force to other tissues and organs Turtle peptide is like a demolition force, how many roads to build, how many roads to dismantle, so as not to let the thief force grow and escape 4 Mobilizing the immune system to inhibit tumor growth The human body has an innate immunity, called nonspecific immunity, which is like swine fever, which is transmitted in pigs and does not infect people There is also an acquired immune system that is stimulated by some viruses and bacteria It is called specific immune system In other words, it's the virus you've been infected with If you infect it again, the body will resist it well without getting sick The immune active peptides in thymosin, interferon, interleukin and plant protein can not only increase immunity, increase immune response of immune organs and phagocytosis of macrophages, improve the resistance of the body to external bacteria and viruses, and reduce the incidence of tumor 5 Antioxidation and radiation damage resistance The human body produces free radicals every day, which are also a group of villains In the human body, there is a set of substances called antioxidant enzymes to specifically clean up these villains, which can protect the immune system of the human body or protect DNA, protein and lipids from the harm of villains and cause cancer Turtle peptide can make "police's business ability stronger" and eliminate more damage to human body caused by villains Some turtle peptides have strong ability to combine with and capture free radicals In addition to scavenging free radicals, peptides can also prevent leukopenia caused by radiation and chemotherapy drugs, and improve the anti-cancer ability of human body Turtle peptide can also prevent the direct damage and oxidative damage of skin caused by ultraviolet rays, improve the survival rate and survival time of irradiated mice, alleviate the inhibition of immune function caused by radiation, and significantly improve the proliferation of lymphocytes 6 Interfering with DNA synthesis of tumor cells Turtle peptide, like an undercover, can combine with the DNA in the tumor, penetrate into the enemy's interior, disintegrate it, prevent the tumor from growing up, and fight with iron ions to prevent the DNA replication of tumor cells, so as to prevent the proliferation and differentiation of tumor cells 7 Promoting apoptosis of tumor cells There are various ways to make cancer cells die For example, to freeze the development cycle of cancer cells at a certain stage is equivalent to that cancer cells destroy themselves and commit suicide Some act on the "lysosome" in cells, which is responsible for dissolving all kinds of foreign macromolecular substances that come into the body and inside the body, which is equivalent to the cell's dissipative organ Tumor cells, like prostate cancer, have high lysosomal activity and will be swallowed or digested by the digestive organs of the cells.
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