Huazhong University of Science and Technology's Nature sub-published article: A novel high-efficiency CT contrast agent based on conjugated polymers facilitates precise diagnosis and treatment of tumors

(Correspondent Yin Mingming) On May 12 , the team of Professor Luo Liang from the National Nanomedicine Engineering Technology Research Center, School of Life Science and Technology, Huazhong University of Science and Technology, developed a conjugated polymer material with an iodine content of up to 84% , which can be used for CT comparison High-efficiency CT imaging can be used to guide precise surgical resection and stereotactic radiotherapy of tumo.

Computed tomography (CT) is one of the most commonly used techniques for disease diagnosis and treatment guidanc.

In this study, the researchers firstly assembled monomeric diiodobutadiyne with template molecules in appropriate spatial arrangement to prepare a conjugated polymer PIDA consisting only of carbon iodine by topological chemical polymerizatio.

At the same time, the nanofibrous properties of PIDA can make it show a significant retention effect in the tiss.

Second, the highly planarized conjugated carbon skeleton of PIDA gives it a deep blue color, so it can be easily distinguished from surrounding tissue by the naked e.

Finally, the researchers applied PIDA to imaging - guided radiotherap.

For a long time, researchers have been pursuing the biomedical application and clinical translation of conjugated polymer materia.

The School of Life of Huazhong University of Science and Technology is the first unit of the pap.

This work is another important achievement of Pr.

Paper link: https://