echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Medical News > Latest Medical News > Hutchison Medicine's CSF-1R inhibitor HMPL-653 capsule was approved for clinical use in China

    Hutchison Medicine's CSF-1R inhibitor HMPL-653 capsule was approved for clinical use in China

    • Last Update: 2021-12-07
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    ArticleMedicine Guanlan

    According to the latest announcement from the Center for Drug Evaluation (CDE) of the National Food and Drug Administration of China, Hutchison Medicine’s HMPL-653 capsule has just received an implied clinical trial approval and plans to develop treatments for advanced malignant solid tumors and giant cell tumors of tendon sheaths (TGCT)


    Image source: CDE official website screenshot

    CSF-1R is the cytokine CSF-1 receptor.


    Speaking of giant cell tumor of tendon sheath, this is a rare tumor with local aggressiveness


    However, for patients with giant cell tumor of tendon sheath, the current main treatment is still surgical resection.


    In addition to its role in tendon sheath giant cell tumors, CSF-1R-mediated signaling pathways also play an important role in the differentiation and survival of mononuclear phagocytes, especially macrophages


    At present, the global pipeline for CSF-1R access is also continuing to be promoted


    Reference materials:

    [1] Center for Drug Evaluation (CDE) of China National Medical Products Administration.


    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.