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Little is known about whether the association between hypertension, brain volume, and dementia will change due to age at the time of diagnosis of hypertension
.
Recently, the heart blood vessels published a research article in the authoritative journal Hypertension, researchers analyzed based on baseline data collected and the UK Biobank period 2006-2010
.
The brain volume of the subjects was measured using brain magnetic resonance imaging from 2014 to 2019
Heart blood vessels
The researchers used hospital admissions, mortality, and self-reported data before 2021 to determine the state of dementia, and used propensity scores to stratify by age at diagnosis of hypertension, and randomly selected a control participant for each hypertensive participant
.
The cohort included 11399 hypertensive patients and 11399 controls for brain volume analysis, and included 124053 hypertensive patients and 124053 controls for dementia analysis
.
In the multivariate analysis, the age at which hypertension was diagnosed was under 35 years old (β (95% CI -10.
It can be seen that the diagnosis of hypertension in young or middle-aged people, but not old age, is associated with a smaller brain volume and an increased risk of dementia
.
.
Original source:
Original source:Xianwen Shang.
