Hypertension: it is found that endogenous polypeptides have therapeutic effect on hypertension

Recently, the reporter learned from Kunming Institute of zoology, Chinese Academy of Sciences that the research team of lairen and Professor Ding Jiuping of Huazhong University of science and technology found that an endogenous peptide in human body has a very good therapeutic effect on hypertension The results were published in the journal hypertension of the American Heart Association Hypertension is the most common chronic disease and the main risk factor of cardiovascular and cerebrovascular diseases The main complications were stroke, myocardial infarction, heart failure and chronic kidney disease With the improvement of living standards, the number of patients with hypertension is increasing year by year, so the drugs for the treatment of hypertension has been the focus of drug research and development The researchers found that an endogenous peptide in human body can selectively act on the β subunit of BK channel, which has a good therapeutic effect on hypertension They further validated the therapeutic effect by using the monkey model of hypertension, and found that the peptide can significantly reduce the diastolic and systolic blood pressure of blood vessels, as well as the blood flow speed Therefore, the peptide may be developed into a new drug for the treatment of hypertension.