Immunity when macrophages release steam

Inflammation is a natural and important response of our immune system to danger signals and tissue damage

How to deal with waste produced by inflammation

A research team led by Professor Gerhard Krönke from Erlangen University's Third Department of Medicine-Rheumatology and Immunology has now succeeded in gaining a better understanding of the basic molecular mechanisms involved

Scientists have been able to prove that the danger signal interleukin 33 released from damaged cells triggers continuous changes in macrophage metabolism, thereby significantly improving its waste disposal capacity

Mitochondrial protection is a new way to treat inflammation

The findings of the FAU team may pave the way for new ways to treat chronic inflammatory diseases

Maria Faas, Natacha Ipseiz, Jochen Ackermann, Stephan Culemann, Anika Grüneboom, Fenja Schröder, Tobias Rothe, Carina Scholtysek, Martin Eberhardt, Martin Kun Böttcher, Philipp Kirchner, Cornelia Stoll, Arrif Ekici, Maximilian Ekici, , Benno Weigmann, Stefan Wirtz, Roland Lang, Joerg Hofmann, Julio Vera, David Voehringer, Alessandro Michelucci, Dimitrios Mougiakakos, Stefan Uderhardt, Georg Schett, Gerhard Krönke.