Int J Cancer: The correlation between sleep time and 22 cancer risks

There has been little research on the correlation between sleep time and cancer risk in specific areas other than breast cancer.
addition, the available results remain unclear and causality remains unclear.
goal of this study is to use the Mendel Randomization (MR) design to study the potential causal relationship between sleep time and cancer as a whole and cancer in specific areas.
researchers screened 367,586 individuals from the UK biobase to assess the correlation between sleep and overall cancer and 22 specific site cancers using single nucleotide polymorphism (SNP) as a tool variable associated with sleep characteristic analysis.
analyzed and repeatedly analyzed in 121,579 individual data from another source.
the correlation between genetic susceptivity and cancer risk of short sleep duration showed that the genetic susceptivity of short sleep time was associated with stomach cancer (advantage ratio of 2.22; 95% CI 1.15-4.30; P=0.018), pancreatic cancer (2.18; 1.32-3.62;; The risk of P-0.002) and colorectal cancer (1.48; 1.12-1.95; P-0.006) was associated with a lower risk; however, it was also associated with a lower risk of multiple myeloma (0.47; 0.22-0.99; P=0.047).
the genetic susceptivity associated with long sleep duration is associated with cancer risk there is evidence that long sleep time genetic susceptivity is associated with pancreatic cancer (OR 0.44; 95% CI 0.25-0.0. There was a lower correlation between the incidence of P-0.005) and kidney cancer (0.44; 0.21-0.90; P-0.025).
, however, none of these correlations were significant in multiple comparative analyses.
, the study did not provide strong evidence to support a causal relationship between sleep duration and overall cancer and cancer risk in specific areas.
needs further study.