Intens Care Med: Distal ischemic adaptation in patients with septic shock

Septic shock is one of the most serious complications of all infections, affecting millions of people
each year.

Recently, a research article was published in Intensive Care Medicine, an authoritative journal in critical care medicine, the purpose of which was to determine whether distal ischemic adaptation (RECO) improves the severity and outcome
of multi-organ failure in patients with septic shock compared with standard treatment.

The RECOO-sepsis trial was a prospective, multicenter, randomized, open-label, parallel trial of adult patients in septic shock in six intensive care units in France
.

Of the 180 randomized patients, 178 completed the trial (RECO group: 87; Control group: 91), and incorporating an intent-to-treat analysis (108 males [60.

In patients with septic shock, from inclusion to day 4, RECO failed to reduce the severity of organ failure by average daily SOFA score.

Original Source:

Martin Cour.