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Interim Analysis Shows Positive Efficacy SGLT2 Inhibitor Early Termination of Phase 3 Clinical Trial

 Last Update: 2022-05-27
 Source: Internet
 Author: User

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resting glucose levels

kidney tubule cells

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On March 17, Eli Lilly and Company and Boehringer Ingelheim jointly announced that the SGLT2 inhibitor empagliflozin for the treatment of chronic kidney disease (CKD) patients was based on the recommendation of an independent data monitoring committee.

CKD is a serious disease of decreased kidney function that affects nearly 850 million people worldwide, and many patients go undiagnosed

Empagliflozin is a once-daily, highly selective inhibitor of sodium-glucose co-transporter 2 (SGLT2) that prevents sugar from being reabsorbed by the kidneys in patients with type 2 diabetes with high blood sugar levels.

References:

[1] Jardiance® phase III EMPA-KIDNEY trial will stop early due to clear positive efficacy in people with chronic kidney disease.

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