Scientists have cultivated mini brain organoids in the laboratory, which can mature like a baby's brain!

February 27, 2021 // - A few days ago, a research report titled "Long-term maturation of human cortical organoids matches key early postnatal transitions" was published in the international journal Nature Neuroscience , from the University of California and other institutions Scientists have cultivated a new type of mini brain organoid in the laboratory through research, which is as mature as a baby's brain.

In the article, the researchers conducted extensive genetic analysis of brain organoids cultivated in the laboratory for up to 20 months, and found that these 3-D organoids follow an internal clock that can guide them Maturity and synchronization with the timeline of human development.

The research in this article may be the driving force for more in-depth research in the later period, and now researchers have proved that these organoids can mature and replicate many aspects of normal human development, and enable them to be used as scientists to study humans in petri dishes.

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Image source: Journalist's Resource

The researchers will then expose these ips cells to a special chemical mixture, which will be affected and made into cells in a certain area of ​​the human brain; over time and under the right conditions, the cells will be affected.

For many years, researchers have been cultivating human brain organoids to study human nervous system and neurodevelopmental disorders, such as epilepsy, autism, and schizophrenia.

Researcher Geschwind said that scientists are very interested in stem cell models for human disease research.

Finally, researcher Aaron Gordon said that relevant research results show that these 3-D brain organoids follow a special internal clock, and their development in the laboratory environment is parallel to the changes in the living body.

Reference materials:

[1] Gordon, A.