Intestinal microbiome disorders may be one of the causes of the inflammatory process in older mice.

When gut bacteria were implanted into young mice, it was found that chronic inflammation in older adults gradually occurred in young mice.
and chronic inflammation is closely related to geriatric diseases such as stroke, dementia and cardiovascular disease.
the research from Dr Floris Fransen of the University medical center in Groningen, the Netherlands, and recently published in the journal Frontiers in Immunology.
previous studies have shown that older people have different intestinal bacteria composition seciatics in the elderly and young people, and that the immune response weakens with age, leading to inflammation.
based on this view, Fransen and his team began to study the potential relationships.
scientists transplanted gut bacteria from older and young conventional mice into young sterile mice, and then analyzed the immune response in their spleen, lymph nodes and small intestine tissue.
, they also analyzed the whole genome gene expression of the small intestine.
found that bacteria transplanted from older mice caused an immune response, rather than a younger conventional mouse.
the results suggest that intestinal microbiome disorders may be one of the causes of the inflammatory process in older mice.
and an imbalance or imbalance in the gut flora can lead to "bad" bacteria having an advantage over "good" bacteria. overgrowth of
bad bacteria can cause increased intestinal wall permeability, allowing toxins to enter the bloodstream, allowing them to reach all parts of the body and cause various adverse reactions.
, for example, microflora disorders can cause inflammatory bowel disease, obesity, diabetes, tumors, anxiety and autism.
based on this, the study suggests that maintaining a healthy state of gut microbiome is important for good health, but unfortunately there is no clear explanation as to why there are differences in intestinal flora in older adults.
, for example, many people think that antibiotic regimens affect the digestive system, but according to Fransen, it cannot be attributed to a single cause: "This may be a combination of factors such as reduced exercise and changes in diet, but it is also part of a natural process."
",""In both humans and mice, changed intestinal microbial composition is associated with inflammation, but what exactly is the relationship still needs to be confirmed in the human body."
" Fransen believes more research is needed in the future to confirm whether the human body and mice have similar effects in this study.
.