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    Home > Active Ingredient News > Infection > Intravenous infusion of broad-spectrum antiviral drugs, the child has skin ulcers!

    Intravenous infusion of broad-spectrum antiviral drugs, the child has skin ulcers!

    • Last Update: 2021-03-22
    • Source: Internet
    • Author: User
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    It is only for medical professionals to read.
    Acyclovir is a broad-spectrum and highly effective antiviral drug.
    It is currently the first choice for the treatment of children with viral encephalitis.
    It can improve the clinical symptoms of children and reduce the incidence of complications.
    .

    However, during the administration of acyclovir, there are occasional adverse reactions of varying severity.

    The following child had serious adverse reactions.

     Case summary The patient, male, 1 month and 4 days, developed fever without obvious cause, with a heat peak of 38.
    3°C and occasional startles.

    Combined examination was diagnosed as: viral encephalitis.

    Acyclovir (20ml of 0.
    9% sodium chloride solution + 0.
    04g of acyclovir) was given intravenous infusion of antiviral therapy, and the acupuncture site was the vein of the back of the right hand.

    On the 7th day after the prognosis of the disease, the skin around the venous acupuncture point on the back of the hand was observed to have redness and swelling, so he changed other acupuncture points.

    On the 10th day of medication, the red and swollen skin had been ulcerated and necrotic; on the 14th day, necrotic blood vessels had been observed.

    Figure 1 The healing process of vascular necrosis and peripheral skin ulceration at the acupuncture site on the back of the right hand of a child (male).

    a~f are the changes of the acupuncture site on the back of the hand of the child on the 10th, 12th, 14th, 24th, 30th, and 36th days after medication.

    Debridement gel + foam dressing, silver ion alginate + foam dressing, and hydrocolloid transparent paste care were performed on the ulcerated skin in time, and the wounds of the children improved.

    Case analysis When acyclovir is used for infant antiviral therapy, it is necessary to monitor the children's adverse reactions and pay close attention to the inflammation of the skin around the acupuncture site.

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