Inventory: new compound drugs approved by FDA in the first half of 2015

About the author: Hou Yingwei, Ph.D in pharmaceutical chemistry, Institute of medicine, Chinese Academy of Medical Sciences, started to carry out research in the Institute of medicine, Chinese Academy of Medical Sciences in 2009 and participated in the research of Bill Gates fund and other projects Since September 2013, he has been engaged in postdoctoral research in school of medicine, Ocean University of China He has published articles in Journal of organizational chemistry, chemistry and biology and other academic journals In the first half of this year, FDA approved 13 kinds of original compound new drugs The list is as follows: it is not hard to see from the above table that these 13 new varieties contain a variety of indications such as cold, Parkinson's disease, HIV, hypertension, diabetes, chronic lung disease, etc Dosage forms also include oral, injection, inhalation and other different routes of administration Let's take a look at the characteristics of these 13 varieties Hycofenix, developed and marketed by mikart Co., Ltd., is used to relieve cough, nasal congestion and other symptoms caused by the common cold, but it is not suggested that it can be used by children under 18 years old Flowtuss is similar to hycofenix in composition and is also mikart's product Because this kind of compound contains opioid receptor agonists, which can form a drug-dependent response similar to morphine, it is not recommended for use in minors Rytary is actually a long-acting oral capsule of carbidopa, a standard treatment drug for Parkinson's disease It is used to treat Parkinson's disease, Parkinson's disease after encephalitis, and Parkinson's disease caused by carbon monoxide or manganese poisoning Parkinson's disease is characterized by a decrease in dopamine levels in the brain Compared with the traditional dopamine preparation, rytary can significantly prolong the maintenance time of dopamine in vivo Duopa was developed by abbvie to treat motor fluctuations in patients with advanced Parkinson's disease Similar to rytary, duopa provides patients with the same active ingredients that are released immediately after oral administration of carbidopa and levodopa, but with a more durable treatment Prestalia is a compound antihypertensive drug developed by symplmed company, which is a mixture of dihydropyridine calcium channel blocker and angiotension converting enzyme inhibitor It is used to treat patients whose blood pressure cannot be effectively controlled by a single drug Prezcobix is used in combination with other antiviral drugs to treat human immunodeficiency virus (HIV) HIV is the cause of acquired immunodeficiency syndrome (AIDS) But prezcobix itself cannot be used to treat HIV or AIDS Glyxambi is a once-a-day oral tablet It has two dosage forms: 10 mg of engliptin / 5 mg of gligliptin and 25 mg of engliptin / 5 mg of gliptin The drug is also the only compound drug of SGLT2 inhibitor (enrglitazin, empagliflozin, bringlingham) and DPP-4 inhibitor (linagliptin, linagliptin, Lilly) in the United States Codeine Phosphote and chloroph niramie maleate is similar to hycofenix and flowtus Evotaz, developed by Bristol Myers Squibb, is a fixed dose compound preparation of atazanavir, cobicistat and other antiviral drugs for the treatment of adult AIDS Avycaz is a combination of cephalosporin and a β - lactamase inhibitor for the treatment of patients aged 18 years or older with the following designated sensitive microorganisms: ⑴ complex intraperitoneal infection (Ciai) with metronidazole; ⑵ complex urinary tract infection (ctui) including pyelonephritis Dutrebis is a fixed dose combination of nucleoside reverse transcriptase inhibitors and integrase chain transfer agents for the treatment of HIV-1 infection, but will not be listed in the United States at present StioltoRespimat was developed by the Buling Yin - Ge Han company as a drug for the treatment of chronic obstructive pulmonary disease (COPD), approved by FDA It is an inhalation spray, which can be used for long-term maintenance treatment of airway obstruction of chronic bronchitis and emphysema, but it is not suitable for the treatment of acute exacerbation of asthma and chronic obstructive pulmonary disease Phoxillumbk4 / 2.5in plastic container is composed of a variety of inorganic salts It is an alternative to continuous renal replacement therapy (CRRT) for drug poisoning caused by the removal of dialysable substances by CRRT Tuzitrasr is similar to hycofenix and fluwtuss in the treatment of cold symptoms The above article is the author's personal opinion and does not represent the position of this website The intellectual property rights of the published content belong to yaozhi.com If you need to reprint, please indicate the source and the link of this article.