Is carmine pigment harmful to human body

Introduction: food is the most basic necessities of people's life, and food safety is a major issue related to the national economy and people's livelihood So, is carmine pigment harmful to human body? Come and have a look with you! Food safety has always been the most important issue in our life, especially baby food safety So, is carmine pigment harmful to human body? Let's introduce the small edition of Baibai safety net! The toxicity of cochineal pigment to human body is LD50: > 19.3g/kg in the oral toxicity test of mice (FAO / who) 1 As an azo compound, carmine is metabolized into β - naphthylamine, α - amino-1-naphthol and other substances with strong carcinogenicity in vivo Carmine and Sudan I banned by EU standards are both azo pigments, Azo compounds can be metabolized into mutagenic precursors, aromatic amines Aromatic amines are further metabolized and activated to become electrophilic products combined with DNA and RNA to form adducts and induce mutations 2 Carmine can be oxidized to produce free radicals, and then produce a series of react ive oxygen species (ROS) with the metabolism of substances in the body ROS attack DNA and cause DNA oxidative damage 3 The toxicology experiment of carmine shows that it has certain carcinogenic and mutagenic effects 4 The synthetic pigment carmine will be polluted by arsenic, lead, copper, phenol, aniline, ether, chloride and other substances in the process of processing, which will cause potential harm to human body 5 The toxicity of carmine to loach is small, but carmine can increase the micronucleus cell rate and nuclear abnormality rate of loach in varying degrees, which indicates that carmine has certain mutagenic effect on Loach red cell, and the above genetic toxicity is the content that carmine is harmful to human body I believe you all know after reading it! If you want to know more about food safety Please pay more attention to Baibai Security Internet bar! Editor in charge: Wang Xiujuan