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Recently, a study published in the Journal of diabetes found that the traditional Chinese medicine herb, Celastrus orbiculatus, may have a potential weight loss effect, and its main ingredient is celastrol The study was conducted by the German Diabetes Research Center (DZD) and the environmental health (http:// Research Center (Helmholtz Zentrum m m ü nchen) According to the researchers, celastrol can activate specific satiety centers in the brain that play a key role in weight control Specifically, Katrin pfuhlmann, the first author of the study, explained that celastrol can reactivate the mechanism of body weight control, which is likely to be cut off in obese people Once this mechanism is cut off, the leptin secreted by the human body will no longer play a role, and naturally people will lose their sense of fullness The function of celastrol is to restore the sensitivity of leptin, so as to restore the sense of satiety According to the guidelines for the prevention and treatment of obesity published by the German Association for obesity research (DAG), patients should lose 5% - 10% of their body mass index every year It turns out that although there are many kinds of diet and lifestyle options available, only a small number of people have achieved their weight loss goals So it is very important to break through the "magic barrier", otherwise it will lead to metabolic disorders or accompanied by type 2 diabetes and other metabolic diseases The researchers observed an average weight loss of 10% in a week by taking celastrol in mice In fact, the consumption of celastrol led to the decrease of food intake In addition, celastrol has been shown not only to significantly reduce body weight, but also to help improve diabetes in obese mice