-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Cardiovascular disease has become more common among HIV - infected individuals with the advent of combination antiretroviral therapy .
In the modern era of combination antiretroviral therapy, the extent of macrovascular disease is unclear .
Aortic dilatation can lead to aortic aneurysm, dissection, and death, and predict heart failure, stroke , and cardiovascular death .
The prevalence and extent of subclinical macrovascular disease in HIV-infected individuals has not been established .
In a study published today in JAHA, the leading journal in the field of cardiovascular disease, researchers aimed to assess the association between aortic root and ascending aorta size, as measured by two-dimensional transthoracic echocardiography, and HIV serostatus.
To determine risk factors for enlarged aorta in HIV-infected men, including levels of circulating inflammatory markers
We performed adjusted multivariate linear and logistic regression analyses using clinical and echocardiographic data from the Multicenter AIDS Cohort Study (MACS)
.
The researchers measured four segments of the subjects' proximal aorta: the aortic annulus, the aortic root at the sinus of Valsalva, the sinotubular junction, and the ascending aorta
HIV infection was associated with greater aortic root (0.
03 cm [95% CI, 0.
002-0.
06 cm]) and ascending aorta (0.
CONCLUSIONS: HIV infection is an independent risk factor for ascending aorta enlargement
.
Lower CD4 T cell counts and higher TNF-α levels were associated with increased aortic diameter in HIV-infected men
HIV infection is an independent risk factor for enlarged ascending aorta
Original source:
Anum S.
