JAHA: Community access pneumonia and cardiovascular event risk for people living with HIV

Hospitalization of non-HIV-infected patients for community-acquired pneumonia (CAP) increases the risk of cardiovascular disease (CVD) events.
recently, researchers in JAHA, an authoritative journal in the field of cardiovascular disease, assessed whether people living with HIV (PLWH) had a higher risk of CVD or death after CAP was hospitalized than individuals who were not infected with HIV.
researchers analyzed data from April 2003 to December 2014 from the U.S. Veterans Aging Cohort Study and used Cox regression analysis to determine whether HIV infection was associated with CVD events and mortality rates between the date of hospitalization and 30 days after discharge, and adjusted for known CVD risk factors.
researchers included 4,384 patients (67 percent of patients.
PLWH was younger, CAP severity was lower and CVD risk factors were lower than in patients with CAP who were not infected with HIV.
in the multivarivariable correction analysis, the CVD risk of PLWH individuals was similar (risk ratio of 0.89; 95% CI was 0.70-1.12) compared to hiv infection, but HIV infection was associated with a higher risk of death (HR was 1.49; 95% CI was 1.16-1.90).
, CAP severity was significantly associated with CVD and 30-day mortality in patients with PLWH and hiv-not-infected patients.
result, the risk of CVD events in PLWH and non-HIV-infected patients was similar after adjusting for known CVD risk factors and CAP severity.
, hiv infection was associated with an increase in death rates 30 days after CAP was hospitalized in a multivarivarial correction model.
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