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    Home > Active Ingredient News > Study of Nervous System > JAHA: The relationship between sleep awakening and hypertension in patients with obstructive sleep apnea

    JAHA: The relationship between sleep awakening and hypertension in patients with obstructive sleep apnea

    • Last Update: 2022-01-08
    • Source: Internet
    • Author: User
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    Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction and is the most common sleep breathing disorder, accounting for 9% to 38% of the general population
    .
    As we all know, OSA can increase heart
    blood vessel disease risk, such as hypertension and coronary heart disease
    .
    Sleep fragmentation caused by repeated arousal is a sign of obstructive sleep apnea (OSA)

    .

    Vascular hypertension

    In community-based studies, sleep fragmentation is associated with high blood pressure, but it is unclear whether this association is manifested in OSA
    .
    Recently, a research article published in JAHA, an authoritative journal in the field of cardiovascular disease, aims to explore whether frequent awakenings during sleep can change the relationship between OSA and hypertension

    .

    The study included 10102 OSA patients and 1614 primary snorers
    .
    Hypertension is defined by direct measurement of blood pressure or
    diagnosis by a doctor
    .
    Spontaneous, respiratory, and motor arousals are obtained through polysomnography

    .
    Logistic regression model was used to estimate the association between OSA and primary snoring patients' wakefulness and the prevalence of hypertension

    .

    diagnosis

    For every 10 units increase in the total arousal index, the total sample (odds ratio [OR] is 1.
    08; 95% CI is 1.
    03-1.
    14; P=0.
    002) and OSA patients (OR is 1.
    10; 95% CI is 1.
    04–1.
    16; P< 0.
    001) The probability of suffering from hypertension increased significantly, but it was not significant in the primary snoring group

    .
    The total arousal index is significantly correlated with the systolic and diastolic blood pressure of the total sample (β=0.
    05 and β=0.
    06; P<0.
    001) and OSA patients (β=0.
    05 and β=0.
    06; P<0.
    01), but in primary snoring Otherwise

    .
    In addition, the researchers also noticed that respiratory events with wakefulness had a greater impact on OSA blood pressure than respiratory events without wakefulness

    .
    The outcome of the study was not related to confounding factors, including apnea hypopnea index and nocturnal hypoxemia

    .

    It can be seen that repeated awakenings during sleep are independently related to the prevalence of hypertension in OSA patients
    .

    Repeated awakening during sleep is independently associated with the prevalence of hypertension in OSA patients
    .

    Original source:

    Original source:

    Rong Ren,et al.
    Association Between Arousals During Sleep and Hypertension Among Patients With Obstructive Sleep Apnea .
    JAHA.
    2022.
    https:// href="https://" target="_blank" rel="noopener">Association Between Arousals During Sleep and Hypertension Among Patients With Obstructive Sleep Apnea

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