Obstructive sleep apnea (OSA) is characterized by recurrent upper airway obstruction and is the most common sleep breathing disorder, accounting for 9% to 38% of the general population
As we all know, OSA can increase heart blood vessel disease risk, such as hypertension and coronary heart disease
Sleep fragmentation caused by repeated arousal is a sign of obstructive sleep apnea (OSA)
In community-based studies, sleep fragmentation is associated with high blood pressure, but it is unclear whether this association is manifested in OSA
Recently, a research article published in JAHA, an authoritative journal in the field of cardiovascular disease, aims to explore whether frequent awakenings during sleep can change the relationship between OSA and hypertension
The study included 10102 OSA patients and 1614 primary snorers
Hypertension is defined by direct measurement of blood pressure or diagnosis by a doctor
Spontaneous, respiratory, and motor arousals are obtained through polysomnography
Logistic regression model was used to estimate the association between OSA and primary snoring patients' wakefulness and the prevalence of hypertension
For every 10 units increase in the total arousal index, the total sample (odds ratio [OR] is 1.
08; 95% CI is 1.
002) and OSA patients (OR is 1.
10; 95% CI is 1.
16; P< 0.
001) The probability of suffering from hypertension increased significantly, but it was not significant in the primary snoring group
The total arousal index is significantly correlated with the systolic and diastolic blood pressure of the total sample (β=0.
05 and β=0.
001) and OSA patients (β=0.
05 and β=0.
01), but in primary snoring Otherwise
In addition, the researchers also noticed that respiratory events with wakefulness had a greater impact on OSA blood pressure than respiratory events without wakefulness
The outcome of the study was not related to confounding factors, including apnea hypopnea index and nocturnal hypoxemia
It can be seen that repeated awakenings during sleep are independently related to the prevalence of hypertension in OSA patients
Original source:Original source:
Rong Ren,et al.
Association Between Arousals During Sleep and Hypertension Among Patients With Obstructive Sleep Apnea .
https:// href="https://" target="_blank" rel="noopener">Association Between Arousals During Sleep and Hypertension Among Patients With Obstructive Sleep Apnea
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