JAMA Netw Open: The effect of supplementing 3 times the standard dose of vitamin D on the neurodevelopment of healthy full-term infants

Vitamin D may be important for neurodevelopment
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However, the optimal dose of vitamin D to promote early brain development is unclear

Vitamin D may be important for neurodevelopment Vitamin D may be important for neurodevelopment

This is a double-blind, interventional randomized clinical trial involving healthy babies born at term between January 1, 2013 and June 30, 2014
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As of May 30, 2016, he had been followed up for two years

Vitamin D

The correlation between vitamin D supplementation and developmental milestones in the two groups

The correlation between vitamin D supplementation and developmental milestones in the two groups

Among the 987 families recruited, 495 infants and toddlers received 400 IU of vitamin D3, and 492 infants and toddlers received 1200 IU of vitamin D3
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A total of 801 families (404 in the 400 IU group and 397 infants in the 1200 IU group) were followed up for 12 months and/or 24 months

There was no difference in the average (SD) adjusted age and stage questionnaire total scores between the two groups at 12 and 24 months.

At 24 months, there were no differences in the average (SD) adjusted externalization domain score, internalization domain score, imbalance domain score, or ability score of infant social and emotional assessment between the 400 IU group and the 1200 IU group

Higher than the standard dose of vitamin D3 doses have no systemic benefit on the neurodevelopment of infants and young children under two

Original source:

Original source:

Tuovinen Soile, Räikkönen Katri, Holmlund-Suila Elisa et al.

VS of High-Dose effect Standard ON-Dose Vitamin D Supplementation of neurodevelopment Healthy Term Infants: A Randomized Clinical Trial JAMA in this message