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JAMA Neurology-Mother taking antiepileptic drugs during pregnancy does not affect children's cognitive ability

 Last Update: 2021-07-27
 Source: Internet
 Author: User

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anti-Epilepsy drugs (ASMs) are one of the most commonly used teratogens

epilepsy

Meador et al.

The risk of teratogens is related to the dose, so understanding the higher exposure risk can guide dose management

manage

Kimford J.

Children also used ASM blood concentration (ABLs) and dose to evaluate the relationship between ASM exposure and WWE children’s neurodevelopment

They are based on the Bailey Infant and Toddler Development Inventory Third Edition (BSID-III) language domain score, which includes 5 domain scores (language, motor, cognition, social emotion and general adaptability), and BSID-III language domain Correlation with ASM blood levels in WWE children in the third quarter

They analyzed the BSID-III assessment of 292 WWE children (median age, 2.

Most WWE are taking lamotrigine and/or levetiracetam

The important significance of this study is that it found that the cognitive performance of 2-year-old children was not different between WWE children taking ASM and children of healthy women

: There is no difference in cognitive performance of 2-year-old children between WWE children taking ASM and children of healthy women

JAMA

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