JAMA: Pregnant women infected with the new crown, the risk of being sent to the ICU has risen sharply by 446%, quadrupling!

At the beginning of the COVID-19 pandemic, the risk of the novel SARS-CoV-2 pathogen to groups of pregnant women was unclear

At the beginning of the COVID-19 pandemic, the risk of the novel SARS-CoV-2 pathogen to groups of pregnant women was unclear

However, international reports vary in the severity of disease resulting from infection with SARS-CoV-2 and the extent and nature of infection with associated adverse pregnancy outcomes .

The Canadian Surveillance of COVID-19 in Pregnancy (CANCOVID-Preg) is Canada's only national surveillance program for SARS-CoV-2 affecting pregnancy

This project aims to promote a comprehensive international understanding of SARS-CoV-2 in pregnancy and generate Canada-specific data to support national and provincial public health policy

As of October 31, 2021, a cumulative total of 8786 pregnancies

As of October 31, 2021, a cumulative total of 8,786 infected pregnancies have been reported in Canada

adverse pregnancy outcomes

adverse pregnancy outcomes

Hospitalizations not related to SARS-CoV-2 were excluded from this analysis

Risk factors for adverse pregnancy outcomes

Risk factors for adverse pregnancy outcomes

Risk factors for severe maternal illness (hospitalization, ICU admission, and oxygen therapy) were analyzed using bivariate mixed-effects log-binomial regression ( Figures 1 and 2 )

Figure 1Figure 1Figure 2Figure 2

More details on hospitalization events are available in patients hospitalized with SARS-CoV-2 infection in British Columbia, Manitoba, Ontario, Quebec, and Nova Scotia (n = 278)

More details about hospitalization events are available

Among patients (n = 55) receiving corticosteroids in British Columbia, Manitoba, Quebec, or Nova Scotia, 49 (89.

antibiotic

The proportion of confirmed cases involving adverse maternal outcomes has changed over the course of the pandemic ( figure 3 )

Figure 3 Figure 3

Adverse perinatal outcomes

Adverse perinatal outcomes

Table 2 presents rates of adverse perinatal outcomes in pregnancies affected by SARS-CoV-2 and compared them with Canadian CIHI-DAD data on adverse pregnancy outcomes during the pandemic (March-September 2021) For comparison, the data excluded pregnancies affected by SARS-CoV-2

In this exploratory surveillance study conducted in Canada from March 2020 to October 2021, SARS-CoV-2 infection during pregnancy was significantly associated with adverse maternal outcomes and increased risk of preterm birth

 

Original source:

Original source:

McClymont E, Albert AY, Alton GD, Boucoiran I, Castillo E, Fell DB, Kuret V, Poliquin V, Reeve T, Scott H, Sprague AE, Carson G, Cassell K, Crane J, Elwood C, Joynt C, Murphy P , Murphy-Kaulbeck L, Saunders S, Shah P, Snelgrove JW, van Schalkwyk J, Yudin MH, Money D; CANCOVID-Preg Team.

McClymont E, Albert AY, Alton GD, Boucoiran I, Castillo E, Fell DB, Kuret V, Poliquin V, Reeve T, Scott H, Sprague AE, Carson G, Cassell K, Crane J, Elwood C, Joynt C, Murphy P , Murphy-Kaulbeck L, Saunders S, Shah P, Snelgrove JW, van Schalkwyk J, Yudin MH, Money D; CANCOVID-Preg Team.
Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes.
JAMA .
2022 May 2.
doi: 10.
1001/jama.
2022.
5906.
Epub ahead of print.
PMID: 35499852.
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