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    Home > Active Ingredient News > Antitumor Therapy > JAMA Sub-Journal: Data of 500,000 people show that radioactive iodine treatment does not necessarily increase the risk of thyroid cancer!

    JAMA Sub-Journal: Data of 500,000 people show that radioactive iodine treatment does not necessarily increase the risk of thyroid cancer!

    • Last Update: 2021-09-29
    • Source: Internet
    • Author: User
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    Hyperthyroidism is a form of thyrotoxicosis, a clinical condition characterized by excessive levels of tissue thyroid hormones


    Hyperthyroidism is a form of thyrotoxicosis, a clinical condition characterized by excessive levels of tissue thyroid hormones


    JAMA

    Researchers used the Medline and Cochrane library electronic databases of medical keywords and text keywords, as well as Emtree's Embase, to screen for studies published in October 2020


    diagnosis

    The main results and measures of the study are the incidence and mortality of cancers exposed to and not exposed to RAI treatment, and the level of activity managed by RAI


    manage

    Results A total of 12 studies including 479,452 participants were included .


    The overall collective cancer incidence rate ratio between exposure to RAI treatment and non-exposure to RAI treatment was 1.


    Use linear and nonlinear models to study the dose-response relationship between radioactive iodine dose and cancer mortality

    However, the confounding of uncontrollable indications and other sources of bias are important limitations of studies comparing RAI exposure and non-exposure


    Breast cancer

    Researchers believe that after RAI treatment for hyperthyroidism, the risk of radiation-induced cancer is very small.


    After RAI treatment of hyperthyroidism, the risk of radiation-induced cancer is very small.


    In summary, this meta-analysis showed that the total pooled cancer risk after exposure to RAI treatment was not significant compared with that of no exposure, and a linear dose-response relationship was observed between RAI treatment and solid cancer mortality


    references:

    Cancer Risk After Radioactive Iodine Treatment for Hyperthyroidism: A Systematic Review and Meta-analysis.


    Cancer Risk After Radioactive Iodine Treatment for Hyperthyroidism: A Systematic Review and Meta-analysis.


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