Japanese chicken embryo cells are used to produce myocardial membrane

Introduction: a research team from the Institute of medical engineering, Tokyo Women's Medical University announced on February 5 that they used the cells that generate chicken heart muscle to develop a cell membrane - myocardial membrane - in a special culture dish This kind of myocardial membrane can perform rhythmic beating naturally Scientists have also managed to combine the two membranes to make their rhythms consistent Based on this cell membrane, various organs can be made by various complex combinations Scientists believe that this technology will become a basic technology of regenerative medicine The research team first cultured the fertilized eggs of chickens At the early stage of the development of the fertilized eggs, the cells that can develop into the heart muscle of chickens in the future were extracted from the embryos After several days of cultivation in a culture dish, the cells arranged in layers into a membrane and jumped up naturally to form a myocardial membrane The research team successfully overlapped the two films, and the beating rhythm of the two films was naturally the same; one film was stimulated by electric current to change its beating rhythm, and the beating of the other film was also changed The team also developed special dishes for this study The protein around the cells that form organs will be damaged when the membrane is cultured in a common culture dish and then peeled off with chemicals To solve this problem, the research team developed a "temperature responsive Petri dish" The inner surface of the culture dish is attached with a layer of high polymer which is sensitive to the temperature change When the cell membrane is successfully cultured, the temperature of the culture dish is reduced, and the cell membrane can be taken off from the culture dish intact At present, the treatment of culturing simple tissues such as cartilage and skin by culturing cells is in clinical trials The research of regenerating damaged tissues and organs by culturing cells is under way, but it is very difficult to cultivate organs composed of many kinds of cells such as heart and liver by this method Based on cell membrane, different kinds of membrane can be combined to produce various complex human organs Therefore, cell membrane technology is a basic technology of regenerative medicine The research team said that in the future, it will carry out research on making human tissues and organs with cell membrane China feed industry information network XMU