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Background: Interferon regulatory factor 8 (IRF8) is a transcription factor that controls not only the development and function of mammalian myeloid hematopoietic cells, but also their function, including their response to interferon-gamma (interferon-gamma) react
Interferon regulatory factor 8 (IRF8) is a transcription factor that controls not only the development and function of mammalian myeloid hematopoietic cells, but also their function, including their response to interferon-gamma (interferon-gamma)
Results: The patient was born and lived in Argentina
Figure 1.
Figure 1.
Figure 2 Peripheral blood leukocyte, hemoglobin, and platelet counts and functions
Figure 2 Peripheral blood leukocyte, hemoglobin, and platelet counts and functions
Table 1 Immunophenotypes of different immune cell subsets in peripheral blood of patients
Conclusions: We describe 4 patients with AR complete IRF8 deficiency
We describe 4 patients with AR complete IRF8 deficiency
Jérémie Rosain, Andrea Bernasconi, Emma Prieto, et al.
Pulmonary Alveolar Proteinosis and Multiple Infectious Diseases in a Child with Autosomal Recessive Complete IRF8 Deficiency.
Journal of Clinical Immunology March 2022.
Pulmonary Alveolar Proteinosis and Multiple Infectious Diseases in a Child with Autosomal Recessive Complete IRF8 Deficiency.
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