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    Home > Active Ingredient News > Study of Nervous System > JNNP: A systematic review and meta-analysis of MRI-guided laser interstitial thermal therapy for drug-resistant epilepsy

    JNNP: A systematic review and meta-analysis of MRI-guided laser interstitial thermal therapy for drug-resistant epilepsy

    • Last Update: 2021-08-14
    • Source: Internet
    • Author: User
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    Epilepsy (epilepsy) is a chronic disease that causes sudden abnormal discharge of brain neurons, leading to transient brain dysfunction


    Epilepsy (epilepsy) is a chronic disease that causes sudden abnormal discharge of brain neurons, leading to transient brain dysfunction


    Intraoperative real-time magnetic resonance imaging (MRI) temperature measurement allows continuous monitoring of the ablation area, and the ablation can be stopped at any time


    Intraoperative real-time magnetic resonance imaging (MRI) temperature measurement allows continuous monitoring of the ablation area, and the ablation can be stopped at any time


    Systematic review and meta-analysis flowchart

    Systematic review and meta-analysis flowchart Systematic review and meta-analysis flowchart

    The following databases were searched: PubMed (1947-November 30, 2020), Embase.


    The following databases were searched: PubMed (1947-November 30, 2020), Embase.


    The square and horizontal line correspond to the postoperative adverse event rate and 95% CI

    The square and horizontal line correspond to the postoperative adverse event rate and 95% CI

    The information collected includes study characteristics (author, publication year, study location, and study design), population characteristics, including demographics, such as age and gender, epilepsy history, such as epilepsy duration, average FU duration, MRI findings, and laser ablation Treatment results


    The information collected includes study characteristics (author, publication year, study location, and study design), population characteristics, including demographics, such as age and gender, epilepsy history, such as epilepsy duration, average FU duration, MRI findings, and laser ablation Treatment results


    A total of 559 DRE patients were included in 28 studies


    Funnel chart analysis of Engel level 1 results

    Funnel chart analysis of Engel level 1 results

    Compared with drug treatment, surgical resection can significantly increase the chance of seizures in patients with DRE


    Compared with drug treatment, surgical resection can significantly increase the chance of seizures in patients with DRE


     

     



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