JNNP: Deep down, under disease: amyotrophy lateral sclerosis - social cognition of otestroid spectrum disorder.

There are clinical and pathological similarities between amyotrophic lateral sclerosis (ALS) and forehead dementia (FTD).
associated with ALS is similar to preleteal dysfunction in behavioral variability FTD (bvFTD), indicating continuity between the two conditions.
amyotrophy lateral sclerosis-frontal temporal lobe spectrum disorder (ALS-FTSD) standards divide ALS patients into: (1) ALS (ALSci) with cognitive impairment, (2) ALS (ALSbi) with behavioral disorders, (3) ALS combined cognitive and behavioral disorders (ALScbi) and (4) ALSFTD.
the authors compared the social cognitive abilities of patients with amyotrophic lateral sclerosis (ALS) and behavioral variability of bvFTD.
social cognition refers to a series of cognitive abilities needed to adapt to behavior in social situations, such as psychological theory, emotional recognition and psychologicalization.
in ALS-FTSD5-9 and bvFTD, social cognitive impairment and executive dysfunction are common.
: 62 participants from two neurology clinics in Brazil and Chile.
conducted comprehensive cognitive tests in 21 ALS patients, 20 bvFTD patients, and 21 healthy controls, including facial mood recognition tests (FERTs), simple mental state tests, positive assessment of vocabulary fluency (F-A-S), digital breadth (direct and back) tests, and Hayling tests.
none of the participants met the criteria for depression or other neurological (such as aphdesxia) or mental illness.
patients with ALS did not experience respiratory dysfunction.
after-the-fact analysis of ALS patients, they were divided into two subgroups: patients without cognitive impairment (ALScn; n=13) and patients with cognitive impairment (ALSci; n=8).
: There was no significant difference in age, gender, and culture between the two groups of subjects.
alS group was similar to the course of the bvFTD patients.
alSci patients performed poorly in fert (p-lt;0.001), faux pas (p-lt;0.004) and Mini-SEA (p-lt;0.002) compared to the control group.
, bvFTD patients performed poorly on performing and social cognitive tests compared to the control group.
patients with ALSci performed similarly to 2000 patients with bvFTD, while patients with ALScn performed similarly with the control group.
the authors support cognitive continuity between ALS and bvFTD, and reveal the cognitive heterogeneity of ALS, expanding its possible neuropsychological characteristics.
Lillo P, Caramelli P, Musa G, et al Inside minds, beneath diseases: social cognition in amyotrophic lateral sclerosis-frontotemporal spectrum disorder Journal of Neurology, Neurosurgery Psython Published Online First: 22 September 2020. doi: 10.1136/jnnp-2020-324302MedSci Original Source: MedSci Original Copyright Notice: All notes on this website "Source: Met Medical" or "Source: MedSci Original" text, images and audio and video materials, copyrighted by Met Medical, not authorized No media, website or individual may be reproduced, and the authorised reprint must include "Source: Metz Medicine".
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