JTO: Professor Fang Wentao's team released the world's first postoperative recurrence prediction model for thymoma

Recently, the research team of China Thymic Oncology Collaborative Group (ChART) led by Professor Fang Wentao, director of the Department of Thoracic Surgery of Shanghai Chest Hospital, published the latest research in the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer (ISLAC) and an international authoritative academic journal in the field of thoracic oncology.

Lung Cancer Management

The Chinese Alliance for Thymoma Research (ChART) retrospective database contains data on patients treated with TET at 18 tertiary referral centers in the People's Republic of China from 1994 to 2012

The Chinese Alliance for Thymoma Research (ChART) retrospective database contains data on patients treated with TET at 18 tertiary referral centers in the People's Republic of China from 1994 to 2012

907 IASLC/ITMIG stage I to IIIa TET patients who underwent R0 resection between 1994 and 2012 were identified from the ChART database

With a median follow-up of 52 months (range, 4-147 months), the 10-year OS rate for all patients was 89.

Table 2 shows the results of univariate analysis of recurrence-free survival

Table 2 shows the results of univariate analysis of recurrence-free survival

In multivariate analysis, only increased WHO histology (NETT vs thymic carcinoma vs B2 and B3 thymoma vs A, AB and B1 thymoma [p < 0.

For the 53 patients who relapsed during follow-up, the median time to relapse was 23 months (range 1-108 months)

For the 53 patients who relapsed during follow-up, the median time to relapse was 23 months (range 1-108 months)

Shanghai Chest Hospital has accumulated rich experience and achievements in the clinical diagnosis, treatment and research of mediastinal diseases, especially thymic tumors

This study established the world's first postoperative recurrence prediction model for thymic tumors, and provided corresponding long-term follow-up recommendations for patients with different recurrence risks, which not only helps in timely detection and treatment, but also reduces unnecessary examinations, allowing patients to Get a safer and better postoperative quality of life

Quality of life diagnosis and treatment guidelines

Original source:

Liu H, Gu Z, Qiu B, Detterbeck FC, Roden AC, Ruffini E, Okumura M, Girard N, Xiang Y, Liu Y, Du Z, Hao Y, Fu J, Zhang P, Pang L, Chen K, Wang Y , Yu Z, Mao T, Fang W; AME Thoracic Surgery Cooperative Group.

A Recurrence Predictive Model for Thymic Tumors and Its Implication for Postoperative Management: a Chinese Alliance for Research in Thymomas Database Study.


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