echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Study of Nervous System > Lancet Neurology: Safety and effectiveness of enhanced blood pressure reduction after successful endovascular treatment of acute ischemic stroke (BP-TARGET): a multicenter, open-label, randomized controlled trial

    Lancet Neurology: Safety and effectiveness of enhanced blood pressure reduction after successful endovascular treatment of acute ischemic stroke (BP-TARGET): a multicenter, open-label, randomized controlled trial

    • Last Update: 2021-04-17
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Endovascular treatment of acute ischemic stroke has shown great efficacy, with a reperfusion rate of over 80%.


    Stroke, vascular biggest challenge in acute ischemic stroke study now is not just reperfusion, also includes ischemia-reperfusion injury, including the blood-brain barrier damage, cerebral edema and cerebral parenchymal hemorrhage.


    Between June 21, 2017 and September 27, 2019, the four participating stroke centers recruited a total of 324 patients: 162 patients were randomly assigned to the intensive target group, and 162 patients were assigned to the standard target group.



    Within 24-36 hours after reperfusion, 65 (42%) of the 154 patients in the enhanced target group and 68 (43%) of the 157 patients in the standard target group were observed on brain CT.


    Compared with the standard treatment systolic blood pressure goal, the results in this article have no evidence that the intensive strategy of reducing the systolic blood pressure to 100-129mmHg within 24-36 hours in patients with acute ischemic stroke after successful endovascular treatment is effective in reducing imaging intraparenchymal bleeding Any impact.


    There is no evidence that the intensive strategy of reducing the systolic blood pressure to 100-129mmHg in patients with acute ischemic stroke within 24-36 hours after successful endovascular treatment has any effect on reducing imaging intraparenchymal bleeding.


    Mazighi, MikaelMazighi, Mikael et al.
    Safety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial.
    The Lancet Neurology, Volume 20, Issue 4 , 265-274 Safety and efficacy of intensive blood pressure lowering after successful endovascular therapy in acute ischaemic stroke (BP-TARGET): a multicentre, open-label, randomised controlled trial.


    Leave a message here
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.