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    Home > Active Ingredient News > Antitumor Therapy > Liver Cancer: Redefining the tumor burden of metaphase hepatocellular carcinoma: 7-11 criteria

    Liver Cancer: Redefining the tumor burden of metaphase hepatocellular carcinoma: 7-11 criteria

    • Last Update: 2021-07-27
    • Source: Internet
    • Author: User
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    Hepatocellular carcinoma (HCC) is one of the common malignant tumors


    Hepatocellular carcinoma (HCC) is one of the common malignant tumors


    The study included 632 patients with mid-term HCC treated with first-line TACE from 2007 to 2019


    The study included 632 patients with mid-term HCC treated with first-line TACE from 2007 to 2019


    Among the 632 patients included, based on the criteria of up-to-7, up-to-11, 5-7, and 7 lesions, 70.



    Different standard curative effect ratio

    Multivariate analysis of related factors in patients with imaging response found that AFP>200 ng/mL (OR) = 0.


    Multivariate analysis of related factors in patients with imaging response found that AFP>200 ng/mL (OR) = 0.


    Based on the 7-11 criteria, the median RFS of patients with low, moderate, and high tumor burden were 15.



    7-11 standard RFS and OS

    Multivariate analysis found that age> 60 years (HR = 1.


    Multivariate analysis found that age> 60 years (HR = 1.



    Predictors of OS

    In summary, studies have shown that for TACE-treated HCC patients in the mid-term, the new 7-11 standard better predicts the efficacy and prognosis


    In summary, studies have shown that for TACE-treated HCC patients in the mid-term, the new 7-11 standard better predicts the efficacy and prognosis


    Original source:

    Ya-Wen Hung, I-Cheng Lee, Chen-Ta Chi, et al.


    Ya-Wen Hung, I-Cheng Lee, Chen-Ta Chi, et al.
    Redefining Tumor Burden in Patients with Intermediate-Stage Hepatocellular Carcinoma: The Seven-Eleven Criteria.
    Liver Cancer.
    DOI: 10.
    1159/000517393.
    Published online: July 22 , 2021.


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