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Measurement of Tumor Necrosis Factor (TNF) Lysis of Adenovirus-Infected Cells

 Last Update: 2021-02-21
 Source: Internet
 Author: User

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prothrombin factor 2

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To minimize or prevent the spread of an acute virus infection, the antiviral immune response must detect and lyse virus-infected cells before virus replicates or is released from the host cell. The immune response has developed both innate and specific responses to meet this objective. Virus-infected cells are lysed by cells of the innate immune response such as activated macrophages and natural killer cells, and by cytokines like tumor necrosis factor (TNF) (
1
,
2
). Here, we will discuss methods we developed to measure the cytotoxic capacities of TNF against adenovius-infected cells.

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