Mechanism of complications after cord blood transplantation revealed

The reporter learned from the University of Science and Technology of China on July 12 that, for 8 years, the research team of Professor Wei Haiming and Tian Zhigang of the Department of Life Sciences and Medicine of the school and the team of Professor Sun Zimin of the Department of Hematology, Affiliated Hospital of the Chinese University of Science and Technology of China, revealed that the pre-implantation after cord blood transplantation The pathological mechanism of PES also provides a treatment strategy for patients with severe PES, which has important guiding significance for further improving the efficacy of non-blood cord blood transplantation and promoting its wide application

Non-blood cord blood transplantation is an important means to cure hematological malignancies, hematopoietic failure diseases, congenital immunodeficiency and some genetic metabolic diseases, and the incidence of chronic graft versus host disease (GVHD) is low and severe after transplantation.

Researchers analyzed the peripheral blood of recipients after non-blood cord blood transplantation and found that there was a significant increase in peripheral blood mononuclear cells in PES patients.

Part of the results of this research provide important practical guidance for the University of Science and Technology of China to propose and implement immunotherapy programs for severely ill patients with new coronary pneumonia