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The existence of amino acids is widely accepted on the pre-life earth, either from endogenous chemical processes or from extraterrestrial matter
This study demonstrated for the first time the usefulness of mechanochemical activation in the synthesis of larger biomolecules such as peptides
Pre-life chemistry studies the chemical transformations of the early Earth (approximately 4.
It is generally believed that from the original chemical inventory, more complex molecules emerged from chemical evolution, which subsequently led to life
The reaction conditions considered feasible are the water medium, the interaction of the water/rock interface, and the solid environment without water
On the earth before the origin of life, the sources of mechanical energy may include impacts, erosion, weathering, tectonics and earthquakes, and the geothermal environment provides the local thermal energy input
The formation of peptide bonds is one of the key chemical transformations in the field of pre-life chemistry
Researchers from the Reserve Bank of India: Dr.
The research team found that in the presence of minerals such as titanium dioxide and silicon dioxide, mechanochemical ball milling of glycine can form glycine oligomers
Experiments with diketopiperazine (DKP), diglycine and triglycerides show that the formation of peptide bonds by mechanochemistry is a dynamic and reversible process, which simultaneously generates and destroys peptide bonds
It is worth noting that the ball milling of the mixture of glycine and l-alanine resulted in the formation of their heterooligopeptides
The long glycine oligomers obtained through mechanochemical pathways may provide a more diverse library of pre-terrestrial biological peptides through chemical modification (such as α-alkylation)
"The origin of life is one of the most important issues in science and requires interdisciplinary research methods
In December 2020, the asteroid samples were brought back to Earth for the first time, and more samples are expected to be brought back in 2023
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