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Cao Yunxia introduced melatonin is a broad-spectrum and efficient antioxidant.
previous studies have shown that melatonin can promote the development of immature ovarian cells during the ovulation cycle.
, there have been few studies on whether melatonin promotes the freezing effect of human ovarian cells and their molecular mechanisms.
researchers, by establishing an efficient antioxidant human ovary ovary technique, significantly inhibited the low temperature damage suffered by the eggs during freezing and thawing, effectively maintained the quality of the eggs after freezing and thawing, and achieved good development results.
by detecting mitochondrial function, microstructivity, permeability of egg cell membranes, developmental ability and molecular mechanisms of ovarian cells after thawing, melatonin can be found to improve the freezing effect.
, the first author of this article, said that in recent years, human egg freezing has set off a boom in the field of assisted reproductive technology.
technology can help women who have lost ovarian function due to premature ovarian aging, pelvic disease, tumor surgery or radiation, chemotherapy, etc. to solve fertility problems.
it is understood that the study explores the effects of melatonin on the development potential of ovarian cells and their molecular mechanisms, and provides a new technical and theoretical basis for establishing a safe and efficient technical system for the cryopresetic preservation of human eggs.
, the research results provide ideas for the establishment of human egg bank, and are a new breakthrough in human assisted reproductive technology.
(Reporter Yan Lihai, Correspondent Hui Jirong)