Mercadon Anaesthetic Awakening Period Muscle Loose Antagonist Rookie - Shu's Sweet

Sugammadex sodium is the first selective antagonist developed by Mercado PharmaceuticalsFirst listed in Sweden in 2008, it was used to reverse muscle relaxation symptoms caused by aloof ammonium or viku bromideIn 2010 and 2015, Mercado Pharmaceuticals filed applications with Japan and the United States, and on December 15, 2015, it was approved for listing by the U.SFDA under the name Bridionmuscle relaxation drugs in clinical general anesthesia is very widely used, in some special types of surgery, such as laparoscopic surgery, but also need deep muscle relaxation, so as to provide a good operating space for the operator, and anaesthetic awakening period deep muscle relaxation if not complete antagonism will bring many clinically related complications, such as carbon dioxide accumulation, lung failure, respiratory obstruction, and even rescue, re-intubationIn the past, people used the new sminga attoin combination to antagonise non-depolarized muscle loose medicine, but there are also certain disadvantages, such as may induce asthma, arrhythmia, not suitable for glaucoma patients, and shu more glucan appearance is like an antagonist new starShumore glucose is the starting raw material of gamma-cyclodextrin, in turn by the bromine generation, sulfur etherization reaction to produce more sodium sucrose coarse powder, and then further refined to obtain salysin-sodium sulpridasThe effect is better than acetylcholinesterase inhibitors for non-polarized muscle pine drugs such as ropobromandaum and Viku bromumumThe number of neuromuscular blocking drugs combined with niacin receptors at the nerve muscle joints is reduced by the formation of a composite compound in the plasma by the neuromuscular blocking drug Roku brominated ammonium or Viku bromumthane, thus antagonising the neuromuscular block induced by the amonium roko bromine or viku bromumumCan be used to combine organ dysfunction, severe muscle weakness, difficult airways and special population patientsThere were fewer clinical studies in children under 2 years of age, pregnant women and lactating womenShugen glucan has better tolerance and safety, but clinical should be alert to its potential severe allergic reactions, the extension of the QT interstitity, the increased risk of bleeding and neurotoxicitymore expensive, so in clinical work to save the economic cost of patients, some people have suggested whether to reduce the dose application, but clinical studies show that reducing the dose may increase the possibility of muscle antagonism failure, that is, there may be a single muscle recovery, resulting in adverse consequencesTherefore, it is recommended to use muscle loose monitoring in clinical work to accurately assess the amount of saccharineRapid muscle antagonists can bring many follow-up benefits, such as shortening the recovery cycle of patients, speeding up surgical turnover, and improving patient satisfactionstudies compared the safety and effectiveness of schucanticand sugar with Xinsyn's effect on adult muscle pine reversalA total of 4,206 patients were covered in 41 studies, with the average time of the shochu glucan reversal being only 2min, compared with 12.9min for Xinsmin And the complications of shuxin glucan group were significantly better than the occurrence of Xinsming, taschar, postoperative nausea and vomiting, the incidence of muscle loose residue severity decreased significantly Starting in the second half of 2019, many hospitals began to use saccharine clinically, and in patients who have already used it, muscle resuscent is generally better and safer, but the drug is not yet covered use of saccharides postoperative antagonists can increase the ratio of 4 bunches of stimulation (train-of-four ratio, TOFr) and shorten the time of tubing It can significantly reduce the consumption of related medical resources, is a more cost-effective and even cost-effective option, with better effectiveness and safety This drug into the domestic clinical soon, for some types of surgery patients, such as plastic surgery, difficult airway surgery, etc , can avoid postoperative gas cut or the occurrence of bleeding at the surgical site, both for the patient's life safety and rapid recovery provides a good guarantee, but also the latest compound anesthesia discipline to the development of the perioperative discipline purposes At the end of 2018, domestic enterprises including applications for approval include Colum Pharmaceuticals, Hengrui Pharmaceuticals, Hebei Zhiheng and so on references: A-M Hristovska, P Duch, M Allingstrup, A Afshari The Comparative Efficacy and Safety of Sugammadex and Neostigmine in Reversing Neuromuscular Blockade in Adults A Cochrane Systems Review With Meta-Analysis and Trial Analysis Anaesthesia, 2018, 73 (5), 631-641 original title: Anesthesia , Anaesthetic Awakening Muscle Loose Antagonist Rookie - Shu's More Glucan