Metabolism: Diabetes, blood sugar control and COVID-19 hospitalization risk.

In a recent study published in Metabolic Diseases, the authoritative journal Metabolism-Clinical and Test, researchers aim to assess the forward-looking link between diabetes and blood sugar control and COVID-19 hospitalization through a large community-based cohort study.
as part of the UK Biolibrary Prospective Cohort Study, participants (N-337802, aged 56.4-8.1 years and 55.1 per cent of women) were assessed biomedically at baseline.
result of COVID-19 cases requiring hospitalization between 16 March 2020 and 26 April 2020.
follow-up, the researchers recorded 649 COVID-19 patients.
in the multivariate correction analysis, patients with undiagnosed diabetes at baseline (glycation hemoglobin: A1C to 6.5%) (risk ratio: 2.68; 95% confidence interval: 1.6) 6,4.33) and poor control (A1C to 8.6%) undiagnosed diabetics (1.91; 1.04, 3.52) increased the risk of COVID-19.
With the increase of A1C, the risk of COVID-19 increases in dose dependence and persists in the multivariable adjustment model (for each additional SD (0.9%): 1.07; 1.03, 1.11; trend p.lt;0.001).
in this large community-based sample, normally high A1C levels were a risk factor for COVID-19.
blood glucose regulation may play a key role in the immune response in patients with COVID-19.
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