miRNAs: The key to hiding the aging process in the lower cerebros cerebrocephalus.

Scientists at Einstein College of Medicine in New York have found that stem cells in the lower brain control the rate at which the body ages.
the findings in mice may help people find new ways to deal with age-related diseases and extend their lives.
the study was published online In Nature on June 26.
is responsible for regulating many important life processes, such as growth, development, reproduction and metabolism.
study published in Nature in 2013, researchers at Einstein College of Medicine found that the lower cerebros cerebrosus also regulates the aging process throughout the body.
now, scientists have discovered cells in the lower cerebrocephalus that control aging: adult neural stem cells that form new brain neurons.
Dongsheng Cai, professor of molecular pharmacology at the Einstein College of Medicine, said: "Our study shows that the number of neural stem cells in the lower part of the brain naturally decays with age, and this decay accelerates aging.
found that the effects of this neural stem cell attenuation are not irreversible.
that supplementing stem cells or the molecules they produce can slow or even reverse the body's aging process.
study whether neural stem cells in the lower cerebrocephalus have an effect on aging, the researchers first looked at the changes that these cells make during aging in healthy mice.
when mice grow to 10 months of age, the number of lower-level brain stem cells begins to decline, and after a few months common symptoms of aging appear, " he said.
at the age of 2 (for them old age), most of the neural stem cells disappear," Dr. Cai said.
researchers then wanted to find out whether this reduction in stem cells directly caused aging or simply a correlation with aging.
so they selectively interfered with the lower cerebrocephaly nerve stem cells in middle-aged mice and observed the phenomenon.
Cai said: "This interference significantly accelerated the aging of mice, and these lower-level neural stem cells were disturbed earlier than the control group.
"So can lower-level cerebrocephaly supplement neural stem cells fight aging?" To test the problem, the researchers injected lower-brain stem cells into the brains of middle-aged mice (their stem cells have been destroyed) and normal middle-aged mice.
both groups, the treatment slowed or even reversed many of the symptoms of aging.
Cai and his colleagues found that lower cerebrocephaly stem cells play an anti-aging role by releasing microRNA molecules.
miRNA molecules play a key role in gene expression regulation, although they are not involved in protein synthesis.
the lower cerebrocephaly stem cells can be released into the cerebrospinal fluid of mice by miRNAs wrapped in exosomes.
the researchers extracted exosome particles containing miRNAs from lower cerebrocephaly stem cells and injected them into the cerebrospinal fluid of the two experimental mice: middle-aged mice with damaged lower-level cerebrocephaly stem cells and normal middle-aged mice.
the treatment significantly delayed the aging characteristics of both groups of experimental animals, such as muscle endurance, coordination, social behavior, cognitive ability, and so on.
researchers are determining whether specific miRNAs species and other substances secreted by these stem cells can play an anti-aging role, an important step toward slowing aging and treating diseases associated with aging.
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