MMWR: Clinical features and outcomes of laboratory-confirmed SARS-CoV-2-infected adults hospitalized during periods of B.1.617.2 (Delta) and B.1.1.529 (Omicron) variant predominance

Background: In mid-December 2021, the B.
1.
1.
529 (Omicron) variant of SARS-CoV-2 that causes COVID-19 surpassed the B.
1.
617.
2 (Delta) variant to become the dominant strain in California
.

Preliminary reports suggest that the omicron variant is more transmissible and resistant to vaccine neutralization, but causes less severe disease than previous variants

In mid-December 2021, the B.

RESULTS: Adults admitted during Ogilvy's dominance period received the last (full) dose of the COVID-19 primary vaccine series at a higher rate (39.
6% vs.
There are fewer guidelines for treatment of new coronary pneumonia
.

Although fewer intensive care unit (ICU) admissions and invasive mechanical ventilation (IMV) were required during Omicron's predominance, as well as fewer deaths during hospitalization, after stratification by vaccination status , there were no significant differences in ICU admission or invasive mechanical ventilation (IMV)

Figure 737 adults with sars-cov-2 infection died during intensive care unit admission, use of invasive mechanical ventilation, and hospitalization during the omicron variant epidemic, by age group and vaccination status*

Table 2.
Demographics, clinical characteristics, and clinical outcomes of 131 adults infected with SARS-CoV-2 early in the Omicron variant

Conclusions: Vaccination, including escalating doses for those who are fully vaccinated, remains critical to minimizing the risk of serious health consequences in adults infected with SARS-CoV-2
.

Vaccination, including escalating doses for those who are fully vaccinated, remains critical to minimizing the risk of serious health consequences in adults infected with SARS-CoV-2
.

Original source: Modes ME, Directo MP, Melgar M, et al.

Clinical Characteristics and Outcomes Among Adults Hospitalized with Laboratory-Confirmed SARS-CoV-2 Infection During Periods of B.
1.
617.
2 (Delta) and B.
1.
1.
529 (Omicron) Variant Predominance - One Hospital, California, July 15-September 23 , 2021, and December 21, 2021-January 27, 2022Leave a comment here