Molecular Methods for Haemophilus influenzae
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Last Update: 2021-02-13
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Source: Internet
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Author: User
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The species
Haemophilus influenzae
belongs to the genus Haemophilus and the family Pasteurellaceae.
H influenzae
are small, nonmotile, nonspore forming, Gram-negative, pleomorphic rods that range in shape from coccobacilli to long filaments. They require X and V factors (hemin and NAD, respectively) for aerobic growth, and may be facultatively anaerobic (
1
) Encapsulated
H. influenzae
are classified into six antigenically distinct serotypes (a–f), and have a clonal population structure with two major global subdivisions (I and II) (
2
,
3
). Nonencapsulated
H. infuenzae
(NCHi) appear to have a nonclonal population composition, but a broader analysis of NCHi in the future may reveal that the population is not so distinct from encapsulated
H influenzae
(
4
). Both encapsulated
H influenzae
and NCHi exhibit wide genetic diversity (
5
).
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