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M
IR
AGE is a unique in vivo genome editing technique that exploits the inherent instability of inverted repeats (palindromes) in the
Saccharomyces cerevisiae
chromosome. As a technique able to quickly create deletions as well as precise point mutations, it is valuable in applications that require creation of designer strains of this yeast. In particular, it has various potential applications in metabolic engineering, systems biology, synthetic biology, and molecular genetics.